SCHEMBL152253

SCHEMBL152253

ClCOc1ccc(Cl)cc1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.48
APP P05067 1/20 0.48
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
LMNA P02545 1/20 0.44
CYP2A6 P11509 1/20 0.44
DRD4 P21917 3/20 0.44
SCN4A P35499 2/20 0.44
DRD2 P14416 2/20 0.44
DRD3 P35462 2/20 0.44
KCNH2 Q12809 1/20 0.44
NR4A2 P43354 1/20 0.42
ALDH3A1 P30838 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
SOD1 P00441 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25245394 0.93 MAOB (0.54) MAOBAPPCYP1A2CYP2C9CYP2C19
SCHEMBL11656724 0.93 LTA4H (0.44) MAOBAPPCYP1A2CYP2C9CYP2C19
SCHEMBL11770355 0.88 NQO1 (0.47) MAOBAPPCYP1A2CYP2C19LMNA
SCHEMBL1003652 0.80 MAOB (0.50) MAOBAPPCYP1A2CYP2C9CYP2C19
SCHEMBL1345118 0.80 MAOB (0.57) MAOBAPPDRD4DRD2DRD3
SCHEMBL2411188 0.79 DRD4 (0.55) DRD4DRD2DRD3KCNH2ALDH3A1
SCHEMBL5824496 0.79 DRD4 (0.50) MAOBDRD4DRD2DRD3KCNH2
SCHEMBL11610878 0.79 DRD4 (0.49) MAOBDRD4DRD2DRD3KCNH2
SCHEMBL9770319 0.78 DRD4 (0.59) DRD4DRD2DRD3KCNH2ALDH3A1
Hydrochloric Acid SCHEMBL10552381 0.78 MAOB (0.52) MAOBAPPCYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415769-B2 Vinylether compounds and processes for preparing aldehyde compounds and a carboxylate compound therefrom SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-09-16 US disclosed
WO-2024116789-A1 LUBRICATING OIL COMPOSITION 出光興産株式会社 2024-06-06 WO disclosed
WO-2024080214-A1 METHOD FOR PRODUCING α-OLEFIN POLYMER 出光興産株式会社 2024-04-18 WO disclosed
EP-4119535-B1 ACETAL COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND PROCESSES FOR PREPARING ALDEHYDE COMPOUNDS FROM THE ACETAL COMPOUNDS SHINETSU CHEMICAL CO (JP) 2024-02-21 EP disclosed
EP-4119537-B1 VINYLETHER COMPOUNDS, ALDEHYDE COMPOUND, PROCESS FOR PREPARING THE ALDEHYDE COMPOUND AND A CARBOXYLATE COMPOUND THEREFROM SHINETSU CHEMICAL CO (JP) 2023-12-13 EP disclosed
US-11661390-B2 Acetal compounds and processes for preparing thereof, and processes for preparing aldehyde compounds from the acetal compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-30 US disclosed
US-20230062627-A1 ACETAL COMPOUNDS AND PROCESSES FOR PREPARING THEREOF, AND PROCESSES FOR PREPARING ALDEHYDE COMPOUNDS FROM THE ACETAL COMPOUNDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-03-02 US disclosed
US-20230014797-A1 VINYLETHER COMPOUNDS AND PROCESSES FOR PREPARING ALDEHYDE COMPOUNDS AND A CARBOXYLATE COMPOUND THEREFROM SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-19 US disclosed
EP-4119537-A1 VINYLETHER COMPOUNDS, ALDEHYDE COMPOUND, PROCESS FOR PREPARING THE ALDEHYDE COMPOUND AND A CARBOXYLATE COMPOUND THEREFROM Shin-Etsu Chemical Co., Ltd. (JP) 2023-01-18 EP disclosed
EP-4119535-A1 ACETAL COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND PROCESSES FOR PREPARING ALDEHYDE COMPOUNDS FROM THE ACETAL COMPOUNDS Shin-Etsu Chemical Co., Ltd. (JP) 2023-01-18 EP disclosed
US-4394380-A HERBICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-07-19 US disclosed
US-4352808-A FUNGICIDES, BACTERICIDES, ANTIPROTOZOA AGENTS SCHERING CORPORATION (US) 1982-10-05 US disclosed
US-4349545-A Novel erythromycin a derivatives ROUSSEL UCLAF (FR) 1982-09-14 US disclosed
EP-0056319-A2 Substituted pyrimidin-2-ones and the salts thereof NYEGAARD & CO. A/S (NO) 1982-07-21 EP disclosed
EP-0054233-A1 Novel benzo(b)thiophenes, benzo(b)furans, thiochromans and chromans, processes for their preparation and antimicrobial compositions containing them SCHERING CORPORATION (US) 1982-06-23 EP disclosed
US-4315016-A FUNGICIDES IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1982-02-09 US disclosed
EP-0033195-A1 Pyrimidine-2-sulphides and their S-oxides for use in medicine, pharmaceutical compositions containing them, processes for their preparation and such compounds when novel per se NYEGAARD & CO. A/S (NO) 1981-08-05 EP disclosed
US-4125732-A HYPOLIPIDEMIC AMERICAN CYANAMID COMPANY (US) 1978-11-14 US disclosed
US-4124765-A ANTITUMOR ONO PHARMACEUTICAL CO., LTD. (JP) 1978-11-07 US disclosed
US-4036947-A INSECTICIDE, ACARICIDE AND NEMATOCIDE BAYER AKTIENGESELLSCHAFT (DT) 1977-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12415769-B2 Vinylether compounds and processes for preparing aldehyde compounds and a carboxylate compound therefrom MMAB, CYP4F2, ALDH16A1 MAOB 1190/4885APP 3774/4885CYP1A2 104/4885
US-20230062627-A1 ACETAL COMPOUNDS AND PROCESSES FOR PREPARING THEREOF, AND PROCESSES FOR PREPARING ALDEHYDE COMPOUNDS FROM THE ACETAL COMPOUNDS DHPS, AKR1C4, AKR1C2 MAOB 144/4885APP 2073/4885CYP1A2 82/4885
US-20230014797-A1 VINYLETHER COMPOUNDS AND PROCESSES FOR PREPARING ALDEHYDE COMPOUNDS AND A CARBOXYLATE COMPOUND THEREFROM MMAB, CYP4F2, ALDH16A1 MAOB 1190/4885APP 3774/4885CYP1A2 104/4885
US-11661390-B2 Acetal compounds and processes for preparing thereof, and processes for preparing aldehyde compounds from the acetal compounds DHPS, AKR1C4, AKR1C2 MAOB 144/4885APP 2073/4885CYP1A2 82/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.