Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6031757 | 0.86 | SLC2A1 (0.43) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL2859376 | 0.78 | SLC2A1 (0.40) | ALDH1A1GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2859134 | 0.77 | FLT3 (0.43) | ADRB2ADRB1ADRB3ALDH1A1GAA | |
| SCHEMBL2866303 | 0.75 | ALDH1A1 (0.39) | ADRB2ADRB1ADRB3ALDH1A1GAA | |
| SCHEMBL15665536 | 0.74 | CA1 (0.52) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3968437 | 0.71 | GAA (0.50) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL2858304 | 0.71 | RAB9A (0.48) | ADRB2ADRB1ADRB3ALDH1A1GAA | |
| SCHEMBL2860176 | 0.70 | FLT3 (0.44) | ADRB2ADRB1ADRB3ALDH1A1GAA | |
| SCHEMBL2858288 | 0.69 | FLT3 (0.43) | ADRB2ADRB1ADRB3ALDH1A1GAA | |
| SCHEMBL642424 | 0.69 | CA12 (0.56) | ADRB2ADRB1ADRB3ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1642880-B1 | HSP90 FAMILY PROTEIN INHIBITORS | KYOWA HAKKO KIRIN CO LTD (JP) | 2013-09-04 | — | — | EP | disclosed |