Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 11/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 11/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15225276 | 0.92 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1MAPK1 | |
| SCHEMBL2470452 | 0.89 | LSS (0.43) | HSP90AA1HSP90AB1MAPK1 | |
| SCHEMBL15225663 | 0.88 | HSP90AA1 (0.42) | HSP90AA1HSP90AB1 | |
| SCHEMBL15225372 | 0.88 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1MAPK1 | |
| SCHEMBL15225304 | 0.87 | DRD2 (0.44) | HSP90AA1HSP90AB1MAPK1 | |
| SCHEMBL15225405 | 0.86 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1 | |
| SCHEMBL15225168 | 0.86 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1MAPK1 | |
| SCHEMBL15225431 | 0.86 | HSP90AA1 (0.42) | HSP90AA1HSP90AB1MAPK1 | |
| SCHEMBL15225388 | 0.86 | HSP90AA1 (0.51) | HSP90AA1HSP90AB1 | |
| SCHEMBL2470280 | 0.86 | HSP90AA1 (0.48) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2370437-B1 | BICYCLIC PYRAZOLE AND ISOXAZOLE DERIVATIVES AS ANTITUMOR AND ANTINEURODEGENERATIVE AGENTS | NERVIANO MEDICAL SCIENCES SRL (IT) | 2013-09-04 | — | — | EP | disclosed |