Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 9/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4038581 | 0.90 | ALDH1A1 (0.47) | ALDH1A1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL4038676 | 0.88 | ALDH1A1 (0.48) | ALDH1A1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL4043062 | 0.86 | ALDH1A1 (0.58) | ALDH1A1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL1683981 | 0.81 | MAPT (0.41) | ALDH1A1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL4042311 | 0.79 | RECQL (0.46) | ALDH1A1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL4037099 | 0.77 | MAPT (0.52) | ALDH1A1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL1683842 | 0.76 | CYP19A1 (0.48) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2547764 | 0.76 | MAPT (0.39) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4033843 | 0.75 | PRKDC (0.47) | ALDH1A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4041257 | 0.75 | MAPT (0.46) | ALDH1A1RAB9ANPC1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066632-B1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARM CORP (KR) | 2013-09-04 | — | — | EP | disclosed |