Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | RECQL | P46063 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | ECE1 | P42892 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4042311 | 0.91 | RECQL (0.46) | MAPTRECQLGAAGFERECE1 | |
| SCHEMBL4041257 | 0.91 | MAPT (0.46) | MAPTRECQLGAAGFERECE1 | |
| SCHEMBL4038676 | 0.82 | ALDH1A1 (0.48) | MAPTRECQLGAAGFERALDH1A1 | |
| SCHEMBL7811998 | 0.81 | MAPT (0.64) | MAPTRECQLGAAGFERECE1 | |
| SCHEMBL4043062 | 0.78 | ALDH1A1 (0.58) | MAPTALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL15225838 | 0.77 | ALDH1A1 (0.50) | MAPTALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL15225975 | 0.77 | ERN1 (0.51) | ALDH1A1KDM4EHPGDLMNAHSD17B10 | |
| SCHEMBL4039660 | 0.77 | ERN1 (0.49) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL4038581 | 0.75 | ALDH1A1 (0.47) | MAPTGFERALDH1A1POLBKDM4E | |
| SCHEMBL4041644 | 0.73 | NPC1 (0.42) | NPC1RAB9ALMNAERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066632-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | Chong Kun Dang Pharmaceutical Corp. (KR) | 2009-06-10 | — | — | EP | claimed |
| WO-2008038955-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2008-04-03 | — | — | WO | claimed |