Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4033908 | 0.89 | ERN1 (0.55) | ERN1MEN1KMT2AMAPK1TP53 | |
| SCHEMBL4036698 | 0.81 | ERN1 (0.68) | ERN1MEN1KMT2AMAPK1TP53 | |
| SCHEMBL4035630 | 0.78 | ERN1 (0.62) | ERN1 | |
| SCHEMBL15226080 | 0.78 | ERN1 (0.52) | ERN1MEN1KMT2AMAPK1TP53 | |
| SCHEMBL11634342 | 0.77 | MEN1 (0.66) | ERN1MEN1KMT2AMAPK1TP53 | |
| SCHEMBL12767031 | 0.77 | ERN1 (1.00) | ERN1 | |
| SCHEMBL4041509 | 0.76 | ERN1 (0.56) | ERN1ADORA2AGAAPIK3R1PIK3CA | |
| SCHEMBL4042640 | 0.75 | ERN1 (0.49) | ERN1MEN1KMT2AMAPK1TP53 | |
| SCHEMBL2388588 | 0.74 | MAPT (0.64) | ERN1MEN1KMT2AMAPK1TP53 | |
| SCHEMBL4036525 | 0.73 | ERN1 (0.55) | ERN1MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066632-B1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARM CORP (KR) | 2013-09-04 | — | — | EP | disclosed |