Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 4/20 | 0.39 |
| ▸ | SI | P14410 | 4/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15225895 | 0.89 | ERN1 (0.62) | ERN1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4035630 | 0.79 | ERN1 (0.62) | ERN1 | |
| SCHEMBL4036698 | 0.73 | ERN1 (0.68) | ERN1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12767031 | 0.72 | ERN1 (1.00) | ERN1 | |
| SCHEMBL4038574 | 0.72 | ERN1 (0.49) | ERN1KDM4EALDH1A1MAPTTSHR | |
| SCHEMBL1309728 | 0.72 | KDM4E (0.53) | ERN1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL15226080 | 0.70 | ERN1 (0.52) | ERN1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4040519 | 0.70 | ERN1 (0.47) | ERN1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4041509 | 0.69 | ERN1 (0.56) | ERN1GAAADORA2AMGAMSI | |
| SCHEMBL4042642 | 0.69 | ERN1 (0.53) | ERN1ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066632-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | Chong Kun Dang Pharmaceutical Corp. (KR) | 2009-06-10 | — | — | EP | claimed |
| WO-2008038955-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2008-04-03 | — | — | WO | claimed |