Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 10/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.67 |
| ▸ | PGR | P06401 | 5/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | AR | P10275 | 3/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.67 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.67 |
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 4/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15225936 | 0.93 | NR3C1 (0.70) | NR3C1CYP3A4PGRABCB11LMNA | |
| SCHEMBL4208384 | 0.89 | NR3C1 (0.75) | NR3C1CYP3A4PGRABCB11LMNA | |
| SCHEMBL13928683 | 0.89 | NR3C1 (0.75) | NR3C1CYP3A4PGRABCB11LMNA | |
| SCHEMBL13950974 | 0.84 | NR3C1 (0.79) | NR3C1CYP3A4PGRABCB11LMNA | |
| SCHEMBL4216147 | 0.84 | NR3C1 (0.74) | NR3C1CYP3A4PGRABCB11LMNA | |
| SCHEMBL15225616 | 0.84 | NR3C1 (0.74) | NR3C1CYP3A4PGRABCB11LMNA | |
| SCHEMBL12396688 | 0.82 | NR3C1 (0.85) | NR3C1CYP3A4PGRABCB11LMNA | |
| SCHEMBL12398442 | 0.81 | NR3C1 (0.73) | NR3C1CYP3A4PGRABCB11LMNA | |
| SCHEMBL15225970 | 0.81 | NR3C1 (0.64) | NR3C1CYP3A4PGRABCB11LMNA | |
| Mometasone Furoate SCHEMBL25382496 | 0.81 | CYP3A4 (1.00) | NR3C1CYP3A4PGRABCB11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004667-B1 | NOVEL 11 BETA - HYDROXYANDROSTA-4-ENE-3-ONES | SUN PHARMA ADVANCED RES CO LTD (IN) | 2013-09-04 | — | — | EP | disclosed |