Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 9/20 | 0.51 |
| ▸ | PTPRC | P08575 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15226172 | 0.90 | ERN1 (0.47) | ERN1PTPRCPTPN1ALDH1A1 | |
| SCHEMBL4039660 | 0.84 | ERN1 (0.49) | ERN1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL15226073 | 0.83 | ALDH1A1 (0.48) | ERN1ALDH1A1 | |
| SCHEMBL15226080 | 0.82 | ERN1 (0.52) | ERN1KDM4EALDH1A1CYP3A4HPGD | |
| SCHEMBL15225931 | 0.81 | ERN1 (0.53) | ERN1KDM4EMAPK1HSD17B10 | |
| SCHEMBL4043628 | 0.79 | ABCB1 (0.49) | ERN1KDM4EALDH1A1LMNACYP3A4 | |
| SCHEMBL11763981 | 0.79 | ERN1 (0.46) | ERN1KDM4EALDH1A1CYP3A4HPGD | |
| SCHEMBL4041644 | 0.78 | NPC1 (0.42) | ERN1LMNA | |
| SCHEMBL15226011 | 0.77 | ERN1 (0.47) | ERN1ALDH1A1 | |
| SCHEMBL4037099 | 0.77 | MAPT (0.52) | ERN1KDM4EALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066632-B1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARM CORP (KR) | 2013-09-04 | — | — | EP | disclosed |