Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563697 | 0.81 | EPHX1 (0.51) | EPHX2SMN1; SMN2ADRA2APDE4AADRA1A | |
| SCHEMBL7560180 | 0.77 | KMT2A (0.51) | NPSR1EPHX2SMN1; SMN2ADRA2APDE4A | |
| SCHEMBL1698458 | 0.74 | NPSR1 (0.68) | NPSR1EPHX2SMN1; SMN2EPHX1MAPT | |
| SCHEMBL19998148 | 0.73 | KMT2A (0.65) | EPHX2EPHX1KDM4EALDH1A1KMT2A | |
| SCHEMBL17550885 | 0.72 | EPHX1 (0.64) | NPSR1EPHX2SMN1; SMN2EPHX1LMNA | |
| SCHEMBL20911005 | 0.72 | EPHX1 (0.50) | EPHX2SMN1; SMN2ADRA2APDE4AADRA1A | |
| SCHEMBL23135469 | 0.72 | NPSR1 (0.65) | NPSR1EPHX2SMN1; SMN2EPHX1MAPT | |
| SCHEMBL11775074 | 0.72 | PKM (0.50) | NPSR1EPHX2SMN1; SMN2ADRA2APDE4A | |
| SCHEMBL17226492 | 0.71 | SMN1; SMN2 (0.67) | NPSR1EPHX2SMN1; SMN2LMNAMAPT | |
| SCHEMBL12424272 | 0.71 | ALDH1A1 (0.48) | NPSR1EPHX2SMN1; SMN2ADRA2AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1616859-B1 | Substituted cyclohexyl carboxylic acid compounds | SEIKAGAKU KOGYO CO LTD (JP) | 2013-09-04 | — | — | EP | claimed |