SCHEMBL152306

SCHEMBL152306

Cc1cccc(C)c1C(=O)C(C[PH2]=O)C(=O)c1c(C)cccc1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.38
TDP1 Q9NUW8 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
GPR52 Q9Y2T5 1/20 0.34
TSHR P16473 1/20 0.33
F2R P25116 1/20 0.33
ALDH1A1 P00352 3/20 0.32
HPGD P15428 3/20 0.32
KDM4E B2RXH2 2/20 0.32
HSD17B10 Q99714 2/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
NFKB1 P19838 1/20 0.32
CYP2C19 P33261 1/20 0.32
ALOX12 P18054 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2499316 0.81 KDM4E (0.36) L3MBTL1SMN1; SMN2ALDH1A1HPGDKDM4E
SCHEMBL19873182 0.77 L3MBTL1 (0.38) L3MBTL1TDP1SMN1; SMN2GPR52F2R
SCHEMBL152304 0.74 L3MBTL1 (0.36) L3MBTL1TDP1GPR52F2RALDH1A1
SCHEMBL10137794 0.71 FFAR1 (0.45) L3MBTL1TDP1GPR52TSHRALDH1A1
SCHEMBL3397248 0.70 L3MBTL1 (0.40) L3MBTL1TDP1GPR52ALDH1A1HPGD
SCHEMBL5994217 0.68 L3MBTL1 (0.39) L3MBTL1TDP1GPR52ALDH1A1HPGD
SCHEMBL27573925 0.68 L3MBTL1 (0.39) L3MBTL1TDP1SMN1; SMN2GPR52F2R
SCHEMBL5997921 0.68 KMT2A (0.35) L3MBTL1TDP1SMN1; SMN2F2RALDH1A1
SCHEMBL502187 0.68 ALDH1A1 (0.46) L3MBTL1TDP1GPR52TSHRF2R
SCHEMBL30378504 0.67 L3MBTL1 (0.41) L3MBTL1TDP1GPR52TSHRF2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2428540-B1 Coating composition SHINETSU CHEMICAL CO (JP) 2018-02-21 EP claimed
WO-2023106283-A1 COLORED RESIN COMPOSITION, COLOR FILTER, AND COLOR FILTER MANUFACTURING METHOD 東レ株式会社 2023-06-15 WO disclosed
EP-2428540-B1 Coating composition SHINETSU CHEMICAL CO (JP) 2018-02-21 EP disclosed
US-8642672-B2 Coating composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-02-04 US disclosed
EP-2428540-A1 Coating composition Shin-Etsu Chemical Co., Ltd. (JP) 2012-03-14 EP disclosed
US-20120059080-A1 COATING COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed