Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 1/20 | 0.52 |
| ▸ | KDM6A | O15550 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12763676 | 1.00 | KDM6B (0.52) | KDM6BKDM6AESR1ESR2PTGS2 | |
| SCHEMBL12763677 | 0.81 | PTPN11 (0.43) | ESR1ESR2PTGS2TP53HSD17B10 | |
| SCHEMBL8373929 | 0.78 | KDM6B (0.77) | KDM6BKDM6AESR1ESR2PTGS2 | |
| SCHEMBL804301 | 0.78 | KDM6B (0.50) | KDM6BKDM6AESR1ESR2PTGS2 | |
| SCHEMBL16741949 | 0.73 | TP53 (0.49) | TP53HSD17B10NPSR1MAPTALDH1A1 | |
| SCHEMBL1296601 | 0.71 | KDM6B (0.78) | KDM6BKDM6AESR1ESR2PTGS2 | |
| SCHEMBL8964777 | 0.71 | KDM6B (0.61) | KDM6BKDM6APTGS2TP53HSD17B10 | |
| SCHEMBL29103202 | 0.70 | CHRNB4 (0.61) | TP53MAPTP2RY14CHRNB4CHRNA3 | |
| SCHEMBL28336793 | 0.70 | CHRNB4 (0.61) | TP53MAPTP2RY14CHRNB4CHRNA3 | |
| SCHEMBL7713999 | 0.70 | THRA (0.53) | MAPTKMT2APTPN11KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9523683-B2 | Functionalized polydiacetylene sensors | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-12-20 | — | — | US | claimed |
| US-20150268232-A1 | Functionalized Polydiacetylene Sensors | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2015-09-24 | — | — | US | claimed |
| US-20110059867-A1 | FUNCTIONALIZED POLYDIACETYLENE SENSORS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2011-03-10 | — | — | US | claimed |
| US-9523683-B2 | Functionalized polydiacetylene sensors | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-12-20 | — | — | US | disclosed |
| US-20150268232-A1 | Functionalized Polydiacetylene Sensors | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2015-09-24 | — | — | US | disclosed |
| US-8633140-B2 | Functionalized polydiacetylene sensors | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2014-01-21 | — | — | US | disclosed |
| US-20110059867-A1 | FUNCTIONALIZED POLYDIACETYLENE SENSORS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059867-A1 | FUNCTIONALIZED POLYDIACETYLENE SENSORS | STUB1, PA2G4, SUMO2 | KDM6B 4548/4885KDM6A 4038/4885ESR1 2242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.