Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 5/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10106913 | 0.87 | GRIN2B (0.44) | NPC1RAB9AGRIN2BMAPK14PPARG | |
| SCHEMBL10102011 | 0.82 | NPC1 (0.46) | NPC1RAB9APPARGPPARAMAOB | |
| SCHEMBL10101740 | 0.82 | NPC1 (0.48) | NPC1RAB9APPARGPPARAMAOB | |
| SCHEMBL10102036 | 0.81 | NPC1 (0.50) | NPC1RAB9APPARGPPARAHPGD | |
| SCHEMBL10102080 | 0.78 | NR1H4 (0.37) | GRIN2BPPARGPPARAMRGPRX4SMN1; SMN2 | |
| SCHEMBL10101746 | 0.77 | S1PR1 (0.43) | NPC1RAB9APPARGPPARAMAOB | |
| SCHEMBL10102075 | 0.76 | MAOA (0.44) | NPC1RAB9APPARGPPARAMAOB | |
| SCHEMBL10102038 | 0.76 | SMN1; SMN2 (0.51) | NPC1RAB9APPARGPPARAMAOB | |
| SCHEMBL10102056 | 0.76 | SMN1; SMN2 (0.44) | NPC1RAB9APPARGPPARASMN1; SMN2 | |
| SCHEMBL10101726 | 0.76 | S1PR1 (0.48) | NPC1RAB9APPARGPPARAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8536157-B2 | Non-steroidal compounds | THE UNIVERSITY OF MELBOURNE (AU) | 2013-09-17 | — | — | US | disclosed |