Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 6/20 | 0.45 |
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | PPARA | Q07869 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | AGXT | P21549 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10102301 | 0.89 | RAB9A (0.47) | NPC1RAB9AMAOBPPARGPPARA | |
| SCHEMBL10102056 | 0.88 | SMN1; SMN2 (0.44) | NPC1RAB9APPARGPPARASMN1; SMN2 | |
| SCHEMBL10101740 | 0.87 | NPC1 (0.48) | NPC1RAB9AMAOBPPARGPPARA | |
| SCHEMBL10102038 | 0.86 | SMN1; SMN2 (0.51) | NPC1RAB9AMAOBPPARGPPARA | |
| SCHEMBL10102036 | 0.85 | NPC1 (0.50) | NPC1RAB9APPARGPPARASMN1; SMN2 | |
| SCHEMBL10106852 | 0.85 | PTPN7 (0.46) | NPC1RAB9AMAOBPPARGPPARA | |
| SCHEMBL10101743 | 0.85 | SMN1; SMN2 (0.41) | NPC1RAB9APPARGPPARASMN1; SMN2 | |
| SCHEMBL10101746 | 0.85 | S1PR1 (0.43) | NPC1RAB9AMAOBPPARGPPARA | |
| SCHEMBL10102075 | 0.84 | MAOA (0.44) | NPC1RAB9AMAOBPPARGPPARA | |
| SCHEMBL15255331 | 0.82 | NPC1 (0.42) | NPC1RAB9AMAOBPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8536157-B2 | Non-steroidal compounds | THE UNIVERSITY OF MELBOURNE (AU) | 2013-09-17 | — | — | US | disclosed |
| US-20120046255-A1 | NON-STEROIDAL COMPOUNDS | THE UNIVERSITY OF MELBOURNE of ROYAL PARADE PARKVILLE (AU) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046255-A1 | NON-STEROIDAL COMPOUNDS | PTGES2, PTGES, PTGES3 | NPC1 357/4885RAB9A 3908/4885MAOB 2633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.