SCHEMBL15257537

SCHEMBL15257537

CC1(C)c2ccccc2-c2cc3c4cc(-c5ccc6c(c5)c5ccccc5n6-c5ccccc5)ccc4n(-c4cccc(-c5nc(-c6ccccc6)cc(-c6ccccc6)n5)c4)c3cc21

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ PTGER4 P35408 1/20 0.34
▸ MEN1 O00255 4/20 0.33
▸ KMT2A Q03164 4/20 0.33
▸ KDM4E B2RXH2 3/20 0.33
▸ ALDH1A1 P00352 3/20 0.33
▸ MAPT P10636 3/20 0.33
▸ HPGD P15428 3/20 0.33
▸ LMNA P02545 2/20 0.33
▸ ATM Q13315 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ GLA P06280 1/20 0.32
▸ RXFP1 Q9HBX9 1/20 0.30
▸ PDE10A Q9Y233 1/20 0.30
▸ NTSR1 P30989 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9883234 1.00 PTGER4 (0.34) PTGER4MEN1KMT2AKDM4EALDH1A1
SCHEMBL15257559 0.98 PTGER4 (0.33) PTGER4MEN1KMT2AKDM4EALDH1A1
SCHEMBL15257545 0.95 PTGER4 (0.33) PTGER4MEN1KMT2AKDM4EALDH1A1
SCHEMBL18564277 0.95 KDM4E (0.33) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL25966115 0.95 MEN1 (0.35) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL9883244 0.95 MEN1 (0.36) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL18564274 0.94 KDM4E (0.34) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL17380917 0.94 PTGER4 (0.35) PTGER4KDM4EATML3MBTL1RXFP1
SCHEMBL15805988 0.94 PTGER4 (0.35) PTGER4KDM4EATML3MBTL1RXFP1
SCHEMBL15806107 0.94 PTGER4 (0.35) PTGER4KDM4EATML3MBTL1RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10847727-B2 Compositions for electronic devices MERCK PATENT GMBH (DE) 2020-11-24 — — US disclosed
US-9985220-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2018-05-29 — — US disclosed
US-9985220-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2018-05-29 — — US disclosed
EP-2931698-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2017-09-13 — — EP disclosed
US-20170141328-A1 COMPOSITIONS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2017-05-18 — — US disclosed
US-20170141328-A1 COMPOSITIONS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2017-05-18 — — US disclosed
US-9385335-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-07-05 — — US disclosed
US-9385335-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-07-05 — — US disclosed
US-9324954-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2016-04-26 — — US disclosed
US-9324954-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2016-04-26 — — US disclosed
WO-2015192941-A1 COMPOSITIONS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-12-23 — — WO disclosed
US-20150333274-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-11-19 — — US disclosed
US-20150333274-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-11-19 — — US disclosed
WO-2014090368-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2014-06-19 — — WO disclosed
US-20140014940-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-01-16 — — US disclosed
US-20140014940-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-01-16 — — US disclosed
US-20130240796-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmnH (DE) 2013-09-19 — — US disclosed
US-20130240796-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmnH (DE) 2013-09-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150333274-A1 MATERIALS FOR ELECTRONIC DEVICES CYP2C19, CYP2C9, ECI1 PTGER4 1032/4885MEN1 2584/4885KMT2A 3173/4885
US-20170141328-A1 COMPOSITIONS FOR ELECTRONIC DEVICES EFNA1, EPHA6, EPHB6 PTGER4 434/4885MEN1 1940/4885KMT2A 2418/4885
US-10847727-B2 Compositions for electronic devices EFNA1, EPHA6, EPHB6 PTGER4 434/4885MEN1 1940/4885KMT2A 2418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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