Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15280140 | 0.87 | ACHE (0.47) | RXFP1ACHELMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL806311 | 0.82 | ACHE (0.46) | RXFP1ACHELMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL21120744 | 0.79 | SLC2A1 (0.46) | RXFP1ACHELMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL806517 | 0.79 | ACHE (0.54) | ACHELMNAL3MBTL1POLBMAPT | |
| SCHEMBL7188876 | 0.78 | ALOX5 (0.41) | ACHELMNAPDE10APOLBMAPT | |
| SCHEMBL17919669 | 0.78 | KDM2B (0.47) | — | |
| SCHEMBL28387488 | 0.78 | NCEH1 (0.60) | SMN1; SMN2POLBMAPTNCEH1 | |
| SCHEMBL13772010 | 0.75 | MAPT (0.57) | ACHELMNASMN1; SMN2L3MBTL1POLB | |
| SCHEMBL29350013 | 0.75 | MAPT (0.57) | ACHELMNASMN1; SMN2L3MBTL1POLB | |
| SCHEMBL22135589 | 0.75 | PDE10A (0.44) | LMNASMN1; SMN2PDE10AMAPTPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013137479-A1 | DECAHYDROQUINOXALINE DERIVATIVES AND ANALOGS THEREOF | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-09-19 | — | — | WO | disclosed |