Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.46 |
| ▸ | ADA | P00813 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.43 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19887007 | 1.00 | POLB (0.48) | POLBENPP1P2RY1ADAADORA1 | |
| SCHEMBL15280904 | 0.92 | POLB (0.51) | POLBENPP1P2RY1ADORA1DNPH1 | |
| SCHEMBL15280819 | 0.92 | POLB (0.51) | POLBENPP1P2RY1ADORA1DNPH1 | |
| SCHEMBL24784386 | 0.92 | POLB (0.51) | POLBENPP1P2RY1ADORA1DNPH1 | |
| SCHEMBL19522883 | 0.91 | POLB (0.46) | POLBENPP1P2RY1ADAADORA1 | |
| SCHEMBL23205584 | 0.86 | POLB (0.47) | POLBENPP1P2RY1ADORA1DNPH1 | |
| SCHEMBL15280844 | 0.85 | POLB (0.47) | POLBENPP1P2RY1ADAADORA1 | |
| SCHEMBL19887008 | 0.85 | POLB (0.47) | POLBENPP1P2RY1ADAADORA1 | |
| SCHEMBL14534398 | 0.83 | POLB (0.50) | POLBENPP1P2RY1ADAADORA1 | |
| SCHEMBL12015128 | 0.83 | POLB (0.50) | POLBENPP1P2RY1ADAADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10731159-B2 | Cationic lipid | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-08-04 | — | — | US | disclosed |
| US-20200172903-A1 | ENA ANTISENSE OLIGONUCLEOTIDE FOR INHIBITION OF alpha-SYNUCLEIN EXPRESSION | OSAKA UNIVERSITY (JP) | 2020-06-04 | — | — | US | disclosed |
| US-9803199-B2 | Cationic lipid | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-10-31 | — | — | US | disclosed |
| US-20160257951-A1 | NOVEL LIPID | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-09-08 | — | — | US | disclosed |
| US-8987226-B2 | Modified single-stranded polynucleotides | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-03-24 | — | — | US | disclosed |
| US-20130253038-A1 | Modified Single-Stranded Polynucleotide | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160257951-A1 | NOVEL LIPID | NPC1L1, CETP, LIPC | POLB 394/4885ENPP1 736/4885P2RY1 1522/4885 |
| US-20200172903-A1 | ENA ANTISENSE OLIGONUCLEOTIDE FOR INHIBITION OF alpha-SYNUCLEIN EXPRESSION | SNCA, ENO1, ENY2 | POLB 89/4885ENPP1 13/4885P2RY1 1827/4885 |
| US-10731159-B2 | Cationic lipid | CETP, NPC1L1, LIPA | POLB 404/4885ENPP1 1066/4885P2RY1 1529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.