Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 19/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14063686 | 0.91 | SMN1; SMN2 (0.53) | FOLH1SMN1; SMN2 | |
| SCHEMBL14063688 | 0.87 | FOLH1 (0.59) | FOLH1 | |
| SCHEMBL19352030 | 0.84 | FOLH1 (0.73) | FOLH1SMN1; SMN2 | |
| SCHEMBL7915392 | 0.81 | FOLH1 (0.56) | FOLH1SMN1; SMN2 | |
| SCHEMBL7915383 | 0.81 | FOLH1 (0.56) | FOLH1SMN1; SMN2 | |
| SCHEMBL18807688 | 0.76 | FOLH1 (0.69) | FOLH1 | |
| SCHEMBL16802273 | 0.76 | FOLH1 (0.69) | FOLH1 | |
| SCHEMBL5130089 | 0.76 | NOD1 (0.57) | FOLH1 | |
| SCHEMBL22571854 | 0.76 | FOLH1 (0.68) | FOLH1 | |
| SCHEMBL5130115 | 0.76 | NOD1 (0.57) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8546493-B2 | Multi-armed, monofunctional, and hydrolytically stable derivatives of poly(ethylene glycol) and related polymers for modification of surfaces and molecules | NEKTAR THERAPEUTICS (US) | 2013-10-01 | — | — | US | disclosed |