Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | CPT1A | P50416 | 5/20 | 0.36 |
| ▸ | CPT2 | P23786 | 2/20 | 0.36 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15310193 | 0.92 | S1PR1 (0.72) | S1PR1KMT2AMEN1CPT1ACPT2 | |
| SCHEMBL15310217 | 0.91 | S1PR1 (0.59) | S1PR1KMT2AMEN1CPT1ACPT2 | |
| SCHEMBL15309981 | 0.88 | S1PR1 (0.52) | S1PR1KMT2AMEN1PSMD14CPT1A | |
| SCHEMBL14777535 | 0.87 | S1PR1 (0.51) | S1PR1KMT2AMEN1PSMD14CPT1A | |
| SCHEMBL2224648 | 0.87 | S1PR1 (0.51) | S1PR1KMT2AMEN1PSMD14CPT1A | |
| SCHEMBL15310089 | 0.87 | S1PR1 (0.61) | S1PR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL15310087 | 0.85 | S1PR1 (0.63) | S1PR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL15310091 | 0.84 | S1PR1 (0.59) | S1PR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL14797011 | 0.84 | S1PR1 (0.82) | S1PR1KMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL15310194 | 0.83 | S1PR1 (0.71) | S1PR1KMT2AMEN1CPT1ACPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523960-B1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI SA (FR) | 2013-10-16 | — | — | EP | disclosed |