Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 18/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17975734 | 0.88 | GCGR (0.53) | GCGR | |
| SCHEMBL2306437 | 0.85 | JAK1 (0.38) | GCGR | |
| SCHEMBL4773885 | 0.84 | GCGR (0.41) | GCGR | |
| SCHEMBL3264910 | 0.84 | GCGR (0.41) | GCGR | |
| SCHEMBL15139859 | 0.82 | GCGR (0.39) | GCGR | |
| SCHEMBL2218431 | 0.81 | GCGR (0.47) | GCGR | |
| Bromide SCHEMBL426277 | 0.80 | JAK1 (0.36) | GCGR | |
| SCHEMBL1785167 | 0.80 | GCGR (0.40) | GCGR | |
| SCHEMBL2220970 | 0.80 | GCGR (0.48) | GCGR | |
| SCHEMBL2221425 | 0.78 | PTGS2 (0.37) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351762-B1 | NOVEL PYRIMIDINE DERIVATIVE AND METHOD FOR PRODUCING HMG-CoA REDUCTASE INHIBITOR INTERMEDIATE | KANEKA CORP (JP) | 2013-10-16 | — | — | EP | disclosed |