Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17975734 | 0.89 | GCGR (0.53) | GCGRKIT | |
| SCHEMBL3264910 | 0.88 | GCGR (0.41) | GCGRKIT | |
| SCHEMBL15139859 | 0.86 | GCGR (0.39) | GCGRKIT | |
| SCHEMBL15310067 | 0.84 | GCGR (0.40) | GCGR | |
| SCHEMBL14953476 | 0.84 | JAK1 (0.36) | GCGRKIT | |
| SCHEMBL2220970 | 0.83 | GCGR (0.48) | GCGRKIT | |
| SCHEMBL1785167 | 0.83 | GCGR (0.40) | GCGRKIT | |
| SCHEMBL2218431 | 0.82 | GCGR (0.47) | GCGRKIT | |
| SCHEMBL2221425 | 0.82 | PTGS2 (0.37) | GCGRKIT | |
| Bromide SCHEMBL426277 | 0.82 | JAK1 (0.36) | GCGRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134696-B1 | PROCESSES FOR THE PREPARATION OF STATINS, PARTICULARLY ROSUVASTATIN, AND INTERMEDIATES FOR THE PREPARATION THEREOF | LEK PHARMACEUTICALS (SI) | 2017-05-17 | — | — | EP | disclosed |
| US-8471045-B2 | Synthesis of statins | LEK PHARMACEUTICALS D.D. (SI) | 2013-06-25 | — | — | US | disclosed |
| US-8269001-B2 | Process for the synthesis of HMG-CoA reductase inhibitors | LEK PHARMACEUTICALS D.D. (SI) | 2012-09-18 | — | — | US | disclosed |
| US-20120196333-A1 | SYNTHESIS OF STATINS | LEK PHARMACEUTICALS D.D. (SI) | 2012-08-02 | — | — | US | disclosed |
| EP-1978020-A1 | Processes for the preparation of statins, particularly rosuvastatin, and intermediates for the preparation thereof | LEK Pharmaceuticals D.D. (SI) | 2008-10-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196333-A1 | SYNTHESIS OF STATINS | HMGCR, DHCR7, COASY | GCGR 2504/4885KIT 4655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.