Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 10/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316500 | 0.76 | CA12 (0.31) | — | |
| SCHEMBL17113878 | 0.76 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL3200439 | 0.76 | ALDH1A1 (0.34) | ALDH1A1TDP1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL2067228 | 0.76 | KMT2A (0.46) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL16268103 | 0.67 | KDM4E (0.39) | ALDH1A1TDP1HSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL457459 | 0.67 | TSHR (0.42) | ALDH1A1TDP1TSHRHSD17B10ACHE | |
| SCHEMBL455622 | 0.65 | ALDH1A1 (0.48) | ALDH1A1TDP1TSHRHSD17B10ACHE | |
| SCHEMBL2067226 | 0.64 | ALDH1A1 (0.42) | ALDH1A1TDP1HSD17B10MEN1KMT2A | |
| SCHEMBL10767704 | 0.64 | TDP1 (0.39) | ALDH1A1TDP1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL3200434 | 0.64 | TDP1 (0.38) | ALDH1A1TDP1TSHRHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292606-A1 | Pyrazole derivative, its intermediate, and herbicide containing the same as active ingredient | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2011-03-09 | — | — | EP | disclosed |
| US-7767827-B2 | Pyrazole-1-carboxylate derivatives, process for the production thereof and process for the production of pyrazole derivatives | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2010-08-03 | — | — | US | disclosed |
| US-20100152443-A1 | PYRAZOLE DERIVATIVE, INTERMEDIATE THEREFOR, PROCESSES FOR PRODUCING THESE, AND HERBICIDE CONTAINING THESE AS ACTIVE INGREDIENT | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2010-06-17 | — | — | US | disclosed |
| US-7700786-B2 | Pyrazole derivative, intermediate therefor, processes for producing these, and herbicide containing these as active ingredient | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2010-04-20 | — | — | US | disclosed |
| US-20090162293-A1 | METHODS AND COMPOSITIONS FOR ULTRASOUND IMAGING OF APOPTOSIS | POINT BIOMEDICAL CORPORATION (US) | 2009-06-25 | — | — | US | disclosed |
| EP-1673108-A4 | METHODS AND COMPOSITIONS FOR ULTRASOUND IMAGING OF APOPTOSIS | POINT BIOMEDICAL CORP (US) | 2009-06-03 | — | — | EP | disclosed |
| US-7538215-B2 | Compounds which inhibit leukocyte adhesion mediated by VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 2009-05-26 | — | — | US | disclosed |
| US-20090018345-A1 | PYRAZOLE-1-CARBOXYLATE DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND PROCESS FOR THE PRODUCTION OF PYRAZOLE DERIVATIVES | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2009-01-15 | — | — | US | disclosed |
| US-7413727-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2008-08-19 | — | — | US | disclosed |
| EP-1884512-A1 | PYRAZOLE-1-CARBOXYLIC ESTER DERIVATIVE, METHOD FOR PRODUCING THE SAME AND METHOD FOR PRODUCING PYRAZOLE DERIVATIVE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2008-02-06 | — | — | EP | disclosed |
| EP-0977600-A2 | CONTRAST AGENTS | NYCOMED IMAGING A/S (NO) | 2000-02-09 | — | — | EP | disclosed |
| EP-0971747-A2 | CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 2000-01-19 | — | — | EP | disclosed |
| EP-0963209-A2 | IMPROVEMENTS IN OR RELATING TO DIAGNOSTIC/THERAPEUTIC AGENTS | Marsden, John Christopher (GB) | 1999-12-15 | — | — | EP | disclosed |
| EP-0946202-A2 | CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998047541-A1 | CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1998-10-29 | — | — | WO | disclosed |
| WO-1998018497-A2 | CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1998-05-07 | — | — | WO | disclosed |
| WO-1998018496-A2 | CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1998-05-07 | — | — | WO | disclosed |
| WO-1998018498-A2 | IMPROVEMENTS IN OR RELATING TO DIAGNOSTIC/THERAPEUTIC AGENTS | MARSDEN, JOHN, CHRISTOPHER (GB) | 1998-05-07 | — | — | WO | disclosed |
| WO-1998018500-A2 | IMPROVEMENTS IN OR RELATING TO DIAGNOSTIC/THERAPEUTIC AGENTS | MARSDEN, JOHN, CHRISTOPHER (GB) | 1998-05-07 | — | — | WO | disclosed |
| WO-1998018495-A2 | IMPROVEMENTS IN OR RELATING TO DIAGNOSTIC/THERAPEUTIC AGENTS | MARSDEN, JOHN, CHRISTOPHER (GB) | 1998-05-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152443-A1 | PYRAZOLE DERIVATIVE, INTERMEDIATE THEREFOR, PROCESSES FOR PRODUCING THESE, AND HERBICIDE CONTAINING THESE AS ACTIVE INGREDIENT | CYP51A1, CYP4F11, WEE1 | ALDH1A1 113/4885TDP1 1693/4885TSHR 3081/4885 |
| US-20090018345-A1 | PYRAZOLE-1-CARBOXYLATE DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND PROCESS FOR THE PRODUCTION OF PYRAZOLE DERIVATIVES | WEE1, CYP51A1, CYP4B1 | ALDH1A1 57/4885TDP1 1691/4885TSHR 1959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.