Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6194126 | 0.83 | HSD17B10 (0.44) | ALDH1A1TDP1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL29052275 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TDP1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL8124153 | 0.77 | ALDH1A1 (0.47) | ALDH1A1TDP1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL33832 | 0.77 | TDP1 (0.46) | ALDH1A1TDP1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL7136437 | 0.77 | TDP1 (0.46) | ALDH1A1TDP1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL58862 | 0.76 | MEN1 (0.36) | ALDH1A1TDP1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL457836 | 0.75 | TSHR (0.44) | ALDH1A1TDP1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL1179579 | 0.75 | PDE7A (0.35) | ALDH1A1TDP1TSHRLMNAMAPT | |
| SCHEMBL3042315 | 0.75 | GPR35 (0.42) | ALDH1A1HSD17B10TSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL6129444 | 0.75 | SMN1; SMN2 (0.38) | ALDH1A1TDP1TSHRSMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3380457-A1 | MONOSULFONIC PHENYLTETRAZOLE COMPOUNDS WITH APPLICATIONS | Hangzhou Jennifer Biotech Co., Ltd. (CN) | 2018-10-03 | — | — | EP | claimed |
| US-20180244637-A1 | MONOSULFONIC PHENYLTETRAZOLE COMPOUNDS WITH APPLICATIONS | HANGZHOU JENNIFER BIOTECH CO., LTD. (CN) | 2018-08-30 | — | — | US | claimed |
| WO-2017080443-A1 | MONOSULFONIC PHENYLTETRAZOLE COMPOUNDS WITH APPLICATIONS | HANGZHOU JENNIFER BIOTECH CO., LTD. (CN) | 2017-05-18 | — | — | WO | claimed |
| US-8791102-B2 | Acetanilide sphingosine-1-phosphate receptor antagonists | EXELIXIS, INC. (US) | 2014-07-29 | — | — | US | claimed |
| US-RE43802-E1 | α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors | G.D. SEARLE LLC (US) | 2012-11-13 | — | — | US | claimed |
| US-20110288076-A1 | Sphingosine-1-Phosphate Receptor Antagonists | EXELIXIS, INC. (US) | 2011-11-24 | — | — | US | claimed |
| CN-102256944-A | Sphingosine-1-phosphate receptor antagonists | EXELIXIS INC | 2011-11-23 | — | — | CN | claimed |
| US-RE42889-E1 | α- and β- amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors | G.D. SEARLE LLC (US) | 2011-11-01 | — | — | US | claimed |
| EP-2346821-A1 | SPHINGOSINE-1-PHOSPHATE RECEPTOR ANTAGONISTS | Exelixis, Inc. (US) | 2011-07-27 | — | — | EP | claimed |
| US-7829564-B2 | α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors | G.D. SEARLE LLC (US) | 2010-11-09 | — | — | US | claimed |
| EP-0025190-A2 | Chromogenic compounds and their use as enzymatic substrates | BEHRINGWERKE Aktiengesellschaft (DE) | 1981-03-18 | — | — | EP | claimed |
| US-4244865-A | α hydroxy tripeptide substrates | ABBOTT LABORATORIES (US) | 1981-01-13 | — | — | US | claimed |
| US-4219497-A | Chromogenic substrates | ABBOTT LABORATORIES (US) | 1980-08-26 | — | — | US | claimed |
| US-4217269-A | FOR SPECTROPHOTOMETRIC MEASUREMENT OF PROTEOLYTIC ENZYMES | ABBOTT LABORATORIES (US) | 1980-08-12 | — | — | US | claimed |
| US-4072576-A | Method for studying enzymatic and other biochemical reactions | AB KABI (SW) | 1978-02-07 | — | — | US | claimed |
| US-4060623-A | 1,2,4-Triazole antimycotic compositions and use thereof | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-29 | — | — | US | claimed |
| US-4038404-A | 1,2,4-TRIAZOLE ANTIMYCOTIC COMPOSITIONS AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-26 | — | — | US | claimed |
| US-4036966-A | 1,2,4-Triazole antimycotic compositions and use thereof | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | claimed |
| US-4036967-A | 1,2,4-Triazole antimycotic compositions and use thereof | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | claimed |
| US-4010162-A | Substituted phenanthroline pigments | ALLIED CHEMICAL CORPORATION (US) | 1977-03-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288076-A1 | Sphingosine-1-Phosphate Receptor Antagonists | S1PR1, S1PR2, S1PR3 | ALDH1A1 4114/4885TDP1 2286/4885HSD17B10 3394/4885 |
| US-20180244637-A1 | MONOSULFONIC PHENYLTETRAZOLE COMPOUNDS WITH APPLICATIONS | TST, MPST, SQOR | ALDH1A1 159/4885TDP1 1942/4885HSD17B10 849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.