Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 8/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL577705 | 0.83 | ALDH1A1 (0.36) | MEN1KMT2APOLBALOX5ALDH1A1 | |
| SCHEMBL8146846 | 0.80 | TYR (0.42) | TYRMEN1KMT2APOLBALOX5 | |
| SCHEMBL577373 | 0.78 | ALDH1A1 (0.35) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL693184 | 0.77 | TYR (0.47) | TYRMEN1KMT2APOLBALOX5 | |
| SCHEMBL10220218 | 0.76 | TYR (0.38) | TYRMEN1KMT2APOLBALOX5 | |
| SCHEMBL577515 | 0.76 | KDM4E (0.33) | ALDH1A1KDM4ERAB9ANPC1MAPT | |
| SCHEMBL12732038 | 0.75 | ABCC1 (0.38) | TYRMEN1KMT2APOLBALOX5 | |
| SCHEMBL578194 | 0.74 | PDE10A (0.36) | POLBALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL577561 | 0.72 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1KDM4ERAB9A | |
| SCHEMBL27787206 | 0.72 | TYR (0.44) | TYRMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130273005-A1 | METHODS FOR TREATING HCV | GILEAD SCIENCES, INC. (US) | 2013-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130273005-A1 | METHODS FOR TREATING HCV | HAVCR2, HCCS, LIPC | TYR 2425/4885MEN1 4840/4885KMT2A 4079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.