Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL774435 | 0.85 | KDM4E (0.39) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL2196345 | 0.85 | KDM4E (0.39) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL1691179 | 0.85 | KDM4E (0.39) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL2198163 | 0.82 | KDM4E (0.36) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL1613295 | 0.80 | USP2 (0.50) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL2075658 | 0.80 | KDM4E (0.41) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL14800271 | 0.78 | KDM4E (0.37) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL23151890 | 0.77 | ALDH1A1 (0.46) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL2383262 | 0.77 | ALDH1A1 (0.46) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL4282842 | 0.77 | ALDH1A1 (0.46) | USP2TSHRKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447080-B2 | Viral polymerase inhibitors | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2016-09-20 | — | — | US | disclosed |
| US-9120775-B2 | Viral polymerase inhibitors | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2015-09-01 | — | — | US | disclosed |
| US-20150065445-A1 | Viral Polymerase Inhibitors | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2015-03-05 | — | — | US | disclosed |
| WO-2013152391-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-10-17 | — | — | WO | disclosed |
| US-20130274218-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150065445-A1 | Viral Polymerase Inhibitors | POLR2E, POLM, POLR2H | USP2 3686/4885TSHR 4721/4885KDM4E 4547/4885 |
| US-20130274218-A1 | VIRAL POLYMERASE INHIBITORS | POLR2E, POLM, POLR2H | USP2 3686/4885TSHR 4721/4885KDM4E 4547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.