SCHEMBL15314080

SCHEMBL15314080

N[C@@H](Cc1c[nH]cn1)C(=O)CS

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.31
SLC7A5 Q01650 1/20 0.31
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16280971 0.87 CYP3A4 (0.31) CYP3A4SLC7A5CYP1A2
SCHEMBL15292000 0.87 SLC15A1 (0.40) CYP3A4SLC7A5CYP1A2
SCHEMBL19173325 0.85 CYP3A4 (0.32) CYP3A4SLC7A5CYP1A2
SCHEMBL15214443 0.85 CYP3A4 (0.32) CYP3A4SLC7A5CYP1A2
SCHEMBL16256661 0.85 CYP3A4 (0.32) CYP3A4SLC7A5CYP1A2
SCHEMBL18819939 0.84 CYP3A4 (0.31) CYP3A4SLC7A5CYP1A2
SCHEMBL15781128 0.84 CYP3A4 (0.31) CYP3A4SLC7A5CYP1A2
SCHEMBL13901974 0.84 CYP3A4 (0.31) CYP3A4SLC7A5CYP1A2
SCHEMBL16372520 0.84 CYP3A4 (0.31) CYP3A4SLC7A5CYP1A2
SCHEMBL14319829 0.84 CYP3A4 (0.31) CYP3A4SLC7A5CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8557776-B2 Compounds and methods for 18F labeled agents Bayer Pharma AG (DE) 2013-10-15 US disclosed