SCHEMBL14319829

SCHEMBL14319829

CCC(=O)C(N)Cc1c[nH]cn1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.31
SLC7A5 Q01650 1/20 0.31
NOS2 P35228 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13901974 1.00 CYP3A4 (0.31) CYP3A4SLC7A5NOS2CYP1A2
SCHEMBL18819939 1.00 CYP3A4 (0.31) CYP3A4SLC7A5NOS2CYP1A2
SCHEMBL1117817 0.88 SLC15A1 (0.33)
SCHEMBL15292000 0.87 SLC15A1 (0.40) CYP3A4SLC7A5CYP1A2
SCHEMBL16256661 0.85 CYP3A4 (0.32) CYP3A4SLC7A5NOS2CYP1A2
SCHEMBL15214443 0.85 CYP3A4 (0.32) CYP3A4SLC7A5CYP1A2
SCHEMBL19173325 0.85 CYP3A4 (0.32) CYP3A4SLC7A5CYP1A2
SCHEMBL14693191 0.85 CPB2 (0.31)
SCHEMBL18408792 0.85 LTA4H (0.36)
Histidine SCHEMBL23756735 0.84 SLC7A5 (0.42) CYP3A4SLC7A5CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160039850-A1 SYSTEM FOR DELIVERING THERAPEUTIC AGENTS INTO LIVING CELLS AND CELLS NUCLEI SABAG-RFA LTD. (IL) 2016-02-11 US disclosed
US-20080004234-A1 System for delivering therapeutic agents into living cells and cells nuclei SEGEV LABORATORIES LIMITED (IL) 2008-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160039850-A1 SYSTEM FOR DELIVERING THERAPEUTIC AGENTS INTO LIVING CELLS AND CELLS NUCLEI NFATC1, KPNA2, KPNA6 CYP3A4 4877/4885SLC7A5 1787/4885NOS2 3873/4885
US-20080004234-A1 System for delivering therapeutic agents into living cells and cells nuclei RCC1, NUMA1, ACIN1 CYP3A4 4440/4885SLC7A5 2256/4885NOS2 2696/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.