Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 2/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12761403 | 0.86 | MEN1 (0.46) | MEN1KMT2ATLR8ALPLMAPK14 | |
| SCHEMBL15314588 | 0.85 | MEN1 (0.45) | MEN1KMT2ATLR8MAPK14ALDH1A1 | |
| SCHEMBL12833219 | 0.82 | MEN1 (0.42) | MEN1KMT2ATLR8ALPLMAPK14 | |
| SCHEMBL15314601 | 0.76 | NQO1 (0.43) | MEN1KMT2AMAPK14ALDH1A1SMN1; SMN2 | |
| SCHEMBL12761525 | 0.76 | NQO1 (0.43) | MEN1KMT2AMAPK14ALDH1A1SMN1; SMN2 | |
| SCHEMBL2051020 | 0.76 | ALDH1A1 (0.45) | MEN1KMT2AALPLALDH1A1SMN1; SMN2 | |
| SCHEMBL28284738 | 0.73 | TLR8 (0.62) | MEN1KMT2ATLR8ALDH1A1SMN1; SMN2 | |
| SCHEMBL12832932 | 0.73 | MAPK14 (0.43) | MEN1KMT2AMAPK14ALDH1A1SMN1; SMN2 | |
| SCHEMBL15829537 | 0.71 | AMY1A (0.59) | ALDH1A1SMN1; SMN2HPGDKDM4ENPC1 | |
| SCHEMBL14093047 | 0.68 | TNFRSF1A (0.47) | MAPK14METAP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971595-B1 | CETP INHIBITORS | MERCK SHARP & DOHME (US) | 2013-10-16 | — | — | EP | disclosed |