Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8271284 | 1.00 | POLB (0.57) | POLBSMN1; SMN2HTTALDH1A1L3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL13280491 | 0.98 | POLB (0.55) | POLBSMN1; SMN2HTTALDH1A1L3MBTL1 | |
| SCHEMBL8001584 | 0.85 | POLB (0.41) | POLBSMN1; SMN2HTTALDH1A1L3MBTL1 | |
| SCHEMBL6128607 | 0.83 | NPC1 (0.40) | POLBSMN1; SMN2HTTALDH1A1L3MBTL1 | |
| SCHEMBL1531470 | 0.81 | BRD4 (0.55) | POLBSMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL5499784 | 0.80 | POLB (0.66) | POLBSMN1; SMN2HTTALDH1A1L3MBTL1 | |
| SCHEMBL1538426 | 0.80 | POLB (0.66) | POLBSMN1; SMN2HTTALDH1A1L3MBTL1 | |
| SCHEMBL7951946 | 0.80 | POLB (0.66) | POLBSMN1; SMN2HTTALDH1A1L3MBTL1 | |
| SCHEMBL21575872 | 0.77 | CYP2C19 (0.47) | POLBSMN1; SMN2HTTALDH1A1L3MBTL1 | |
| SCHEMBL338776 | 0.77 | POLB (0.58) | POLBSMN1; SMN2HTTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4399029-A1 | COMPOSITION AND METHOD FOR USE OF 1-ALKYL-5-OXOPYRROLIDINE-3-CARBOXYLIC ACIDS AS COLLECTORS FOR PHOSPHATE AND LITHIUM FLOTATION | Clariant International Ltd (CH) | 2024-07-17 | — | — | EP | claimed |
| US-20230091787-A1 | Composition And Method For Use Of 1-Alkyl-5-Oxopyrrolidine-3-Carboxylic Acids As Collectors For Phosphate And Lithium Flotation | CLARIANT INTERNATIONAL, LTD. (CH) | 2023-03-23 | — | — | US | claimed |
| WO-2023036498-A1 | COMPOSITION AND METHOD FOR USE OF 1-ALKYL-5-OXOPYRROLIDINE-3-CARBOXYLIC ACIDS AS COLLECTORS FOR PHOSPHATE AND LITHIUM FLOTATION | CLARIANT INTERNATIONAL LTD (CH) | 2023-03-16 | — | — | WO | claimed |
| US-8722589-B2 | Use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters as gas hydrate inhibitors with improved biodegradability | CLARIANT FINANCE (BVI) LIMITED (VG) | 2014-05-13 | — | — | US | claimed |
| EP-2028247-A1 | Use of 1-alkyl-5-oxo-pyrrolidine-3-carbolic acid esters as gas hydrate inhibitors with improved biological degradability | CLARIANT INTERNATIONAL LTD. (CH) | 2009-02-25 | — | — | EP | claimed |
| US-20090042747-A1 | Use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters as gas hydrate inhibitors with improved biodegradability | CLARIANT INTERNATIONAL LTD. | 2009-02-12 | — | — | US | claimed |
| EP-4399029-A1 | COMPOSITION AND METHOD FOR USE OF 1-ALKYL-5-OXOPYRROLIDINE-3-CARBOXYLIC ACIDS AS COLLECTORS FOR PHOSPHATE AND LITHIUM FLOTATION | Clariant International Ltd (CH) | 2024-07-17 | — | — | EP | disclosed |
| EP-4399029-A1 | COMPOSITION AND METHOD FOR USE OF 1-ALKYL-5-OXOPYRROLIDINE-3-CARBOXYLIC ACIDS AS COLLECTORS FOR PHOSPHATE AND LITHIUM FLOTATION | Clariant International Ltd (CH) | 2024-07-17 | — | — | EP | disclosed |
| US-20230091787-A1 | Composition And Method For Use Of 1-Alkyl-5-Oxopyrrolidine-3-Carboxylic Acids As Collectors For Phosphate And Lithium Flotation | CLARIANT INTERNATIONAL, LTD. (CH) | 2023-03-23 | — | — | US | disclosed |
| US-20230091787-A1 | Composition And Method For Use Of 1-Alkyl-5-Oxopyrrolidine-3-Carboxylic Acids As Collectors For Phosphate And Lithium Flotation | CLARIANT INTERNATIONAL, LTD. (CH) | 2023-03-23 | — | — | US | disclosed |
| WO-2023036498-A1 | COMPOSITION AND METHOD FOR USE OF 1-ALKYL-5-OXOPYRROLIDINE-3-CARBOXYLIC ACIDS AS COLLECTORS FOR PHOSPHATE AND LITHIUM FLOTATION | CLARIANT INTERNATIONAL LTD (CH) | 2023-03-16 | — | — | WO | disclosed |
| WO-2023036498-A1 | COMPOSITION AND METHOD FOR USE OF 1-ALKYL-5-OXOPYRROLIDINE-3-CARBOXYLIC ACIDS AS COLLECTORS FOR PHOSPHATE AND LITHIUM FLOTATION | CLARIANT INTERNATIONAL LTD (CH) | 2023-03-16 | — | — | WO | disclosed |
| US-10968176-B2 | Pyrrolidone derivatives, oligomers and polymers | NANOSYNTHONS LLC (US) | 2021-04-06 | — | — | US | disclosed |
| US-5525330-A | CONTAINING N-METHYLPYRROLIDONE ALONE OR IN COMBINATION WITHNONCATIONIC ANTIBACTERIAL AGENT | COLGATE PALMOLIVE COMPANY (US) | 1996-06-11 | — | — | US | disclosed |
| EP-0676948-A1 | ANTIPLAQUE, ANTIGINGIVITIS, ANTICARIES ORAL COMPOSITION | Colgate-Palmolive Company (US) | 1995-10-18 | — | — | EP | disclosed |
| US-5368844-A | N-methylpyrrolidone | COLGATE PALMOLIVE COMPANY (US) | 1994-11-29 | — | — | US | disclosed |
| WO-1994013254-A1 | ANTIPLAQUE, ANTIGINGIVITIS, ANTICARIES ORAL COMPOSITION | COLGATE-PALMOLIVE COMPANY (US) | 1994-06-23 | — | — | WO | disclosed |
| WO-1990005131-A1 | POLYMERIZABLE DERIVATIVES OF 5-OXO-PYRROLINE CARBOXYLIC ACID, POLYMERS THEREOF AND METHODS OF PREPARATION | GAF CHEMICALS CORPORATION (US) | 1990-05-17 | — | — | WO | disclosed |
| EP-0069512-B1 | SALTS OF N-SUBSTITUTED-2-PYRROLIDONE-4-CARBOXYLIC ACIDS AS HUMECTANTS | PFIZER INC. (US) | 1986-06-04 | — | — | EP | disclosed |
| EP-0069512-A2 | Salts of N-substituted-2-pyrrolidone-4-carboxylic acids as humectants | PFIZER INC. (US) | 1983-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10968176-B2 | Pyrrolidone derivatives, oligomers and polymers | POF1B, VGF, RAB5IF | POLB 79/4885SMN1; SMN2 3305/4885HTT 1295/4885 |
| US-20230091787-A1 | Composition And Method For Use Of 1-Alkyl-5-Oxopyrrolidine-3-Carboxylic Acids As Collectors For Phosphate And Lithium Flotation | AP2A1, OXGR1, FLOT1 | POLB 3445/4885SMN1; SMN2 3351/4885HTT 2543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.