SCHEMBL15314944

SCHEMBL15314944

COC1CC[C@H](Oc2ccc3c(O)c(NC(=O)c4ccc(O)c(CC=C(C)C)c4)c(=O)oc3c2C)OC1(C)C

nearest known ligand 0.68

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 6/20 0.68
HSP90AB1 P08238 6/20 0.68
MAP1LC3B Q9GZQ8 3/20 0.68
MAP1LC3A Q9H492 3/20 0.68
POLQ O75417 1/20 0.68
ALB P02768 1/20 0.68
KDR P35968 1/20 0.68
ABCG2 Q9UNQ0 1/20 0.68
LMNA P02545 1/20 0.59
KDM4E B2RXH2 1/20 0.59
POLB P06746 1/20 0.56
MAPT P10636 1/20 0.56
RECQL P46063 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21363089 1.00 HSP90AA1 (0.68) HSP90AA1HSP90AB1MAP1LC3BMAP1LC3APOLQ
SCHEMBL19820207 1.00 HSP90AA1 (0.68) HSP90AA1HSP90AB1MAP1LC3BMAP1LC3APOLQ
SCHEMBL22888781 0.93 HSP90AA1 (0.59) HSP90AA1HSP90AB1MAP1LC3BMAP1LC3APOLQ
SCHEMBL21363265 0.93 HSP90AA1 (0.59) HSP90AA1HSP90AB1MAP1LC3BMAP1LC3APOLQ
SCHEMBL19519526 0.93 POLB (0.63) HSP90AA1HSP90AB1MAP1LC3BMAP1LC3APOLQ
SCHEMBL22888461 0.93 HSP90AA1 (0.58) HSP90AA1HSP90AB1MAP1LC3BMAP1LC3APOLQ
SCHEMBL21363045 0.93 HSP90AA1 (0.58) HSP90AA1HSP90AB1MAP1LC3BMAP1LC3APOLQ
SCHEMBL21363095 0.90 HSP90AA1 (0.60) HSP90AA1HSP90AB1MAP1LC3BMAP1LC3APOLQ
SCHEMBL22888438 0.90 HSP90AA1 (0.60) HSP90AA1HSP90AB1MAP1LC3BMAP1LC3APOLQ
SCHEMBL22888876 0.90 HSP90AA1 (0.58) HSP90AA1HSP90AB1MAP1LC3BMAP1LC3APOLQ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130274213-A1 GLYCOSYLATED AMINOCOUMARINS AND METHODS OF PREPARING AND USES OF SAME UNIVERSITY COLLEGE LONDON (GB) 2013-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130274213-A1 GLYCOSYLATED AMINOCOUMARINS AND METHODS OF PREPARING AND USES OF SAME GALE, UGGT1, FUT6 HSP90AA1 3180/4885HSP90AB1 3190/4885MAP1LC3B 2031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.