SCHEMBL15315482

SCHEMBL15315482

CC(C)c1ccc(C(=O)c2ccc(C(C)C)c(C(C)C)c2)cc1C(C)C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.53
GABRB1 P18505 1/20 0.53
PTGS1 P23219 2/20 0.47
PTGS2 P35354 2/20 0.47
ACE2 Q9BYF1 2/20 0.44
HSP90AA1 P07900 3/20 0.43
HSP90AB1 P08238 3/20 0.43
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
TSHR P16473 1/20 0.42
CYP2C19 P33261 1/20 0.42
PDK1 Q15118 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
KDM4E B2RXH2 1/20 0.41
DBH P09172 1/20 0.41
GAA P10253 1/20 0.41
RECQL P46063 1/20 0.41
BCL2 P10415 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12648769 0.90 GABRA1 (0.69) GABRA1GABRB1PTGS1PTGS2CYP3A4
SCHEMBL15315477 0.86 PTGS1 (0.53) GABRA1GABRB1PTGS1PTGS2CYP1A2
SCHEMBL19543002 0.84 GAA (0.59) GABRA1GABRB1ACE2HSP90AA1HSP90AB1
SCHEMBL13816269 0.84 ACE2 (0.61) GABRA1GABRB1PTGS2ACE2HSP90AA1
SCHEMBL13377058 0.84 CYP2A6 (0.47) GABRA1GABRB1ACE2HSP90AA1HSP90AB1
SCHEMBL8416598 0.83 GABRA1 (0.44) GABRA1GABRB1PTGS1PTGS2ACE2
SCHEMBL27025556 0.83 HTT (0.50) GABRA1GABRB1PTGS1PTGS2ACE2
SCHEMBL8655780 0.83 HSP90AA1 (0.62) GABRA1GABRB1PTGS1PTGS2HSP90AA1
SCHEMBL27025558 0.83 HTT (0.50) GABRA1GABRB1PTGS1PTGS2HSP90AA1
SCHEMBL13816274 0.83 PARP10 (0.46) GABRA1GABRB1ACE2HSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170158934-A1 THERMALLY CONDUCTIVE RESIN AND THERMAL INTERFACE MATERIAL COMPRISING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-06-08 US disclosed
US-9499664-B2 Polyimide polymer, polyimide film having the same and polyimide laminate having the same MORTECH CORPORATION (TW) 2016-11-22 US disclosed
US-9371233-B2 Polyamide-imides, graphite films and preparation for the graphite film INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2016-06-21 US disclosed
US-20160122483-A1 POLYIMIDE POLYMER, POLYIMIDE FILM HAVING THE SAME AND POLYIMIDE LAMINATE HAVING THE SAME MORTECH CORPORATION (TW) 2016-05-05 US disclosed
US-9065138-B2 Water soluble binder composition, method of producing the same and electrode for rechargeable battery employing the same SAMSUNG SDI CO., LTD. (KR) 2015-06-23 US disclosed
US-20150166347-A1 POLYAMIDE-IMIDES, GRAPHITE FILMS AND PREPARATION FOR THE GRAPHITE FILM INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2015-06-18 US disclosed
US-20130273423-A1 WATER SOLUBLE BINDER COMPOSITION, METHOD OF PRODUCING THE SAME AND ELECTRODE FOR RECHARGEABLE BATTERY EMPLOYING THE SAME SAMSUNG SDI CO., LTD. (KR) 2013-10-17 US disclosed