Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.62 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.62 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.55 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | DBH | P09172 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11439298 | 0.91 | HSP90AA1 (0.54) | HSP90AA1HSP90AB1PTGS1PTGS2GABRA1 | |
| SCHEMBL383610 | 0.86 | HSP90AA1 (0.60) | HSP90AA1HSP90AB1PTGS1PTGS2GABRA1 | |
| SCHEMBL385514 | 0.86 | HSP90AA1 (0.60) | HSP90AA1HSP90AB1PTGS1PTGS2GABRA1 | |
| SCHEMBL15315482 | 0.83 | GABRA1 (0.53) | HSP90AA1HSP90AB1PTGS1PTGS2GABRA1 | |
| SCHEMBL9556908 | 0.82 | HSP90AA1 (0.57) | HSP90AA1HSP90AB1PTGS1PTGS2GABRA1 | |
| SCHEMBL24603706 | 0.81 | HSP90AA1 (0.69) | HSP90AA1HSP90AB1PTGS1PTGS2GABRA1 | |
| SCHEMBL10368169 | 0.81 | CA12 (0.65) | HSP90AA1HSP90AB1THRBKDM4EGAA | |
| SCHEMBL2853377 | 0.81 | HSP90AB1 (0.64) | HSP90AA1HSP90AB1PTGS1PTGS2GABRA1 | |
| SCHEMBL27959819 | 0.81 | HSP90AA1 (0.64) | HSP90AA1HSP90AB1PTGS1PTGS2GABRA1 | |
| SCHEMBL10428372 | 0.81 | HPGD (0.54) | HSP90AA1HSP90AB1PTGS1PTGS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566423-B1 | Electrophotographic photoconductor | MITSUBISHI CHEM CORP (JP) | 1998-10-21 | — | — | EP | disclosed |
| US-5378567-A | 4-4*-dihydroxybenzophenone and p,p*-dihydroxydiphenylmethane derivatives as monomers; durability; wear resistance | MITSUBISHI KASEI CORPORATION (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0566423-A1 | Electrophotographic photoconductor | Mitsubishi Chemical Corporation (JP) | 1993-10-20 | — | — | EP | disclosed |