Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1815191 | 0.97 | CD274 (0.32) | CD274CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL13988154 | 0.94 | MAPT (0.33) | CD274HTTMAPT | |
| SCHEMBL13988137 | 0.94 | HRH3 (0.31) | CD274POLBKMT2AMAPT | |
| SCHEMBL13988230 | 0.93 | MAPT (0.34) | CD274HTTMAPT | |
| SCHEMBL30175150 | 0.93 | MAPT (0.34) | CD274HTTMAPT | |
| SCHEMBL1046925 | 0.92 | KCNH2 (0.33) | — | |
| SCHEMBL29453300 | 0.92 | KCNH2 (0.33) | — | |
| SCHEMBL13988158 | 0.89 | PRKDC (0.33) | — | |
| SCHEMBL1818315 | 0.89 | KCNH2 (0.33) | MAPT | |
| SCHEMBL1044369 | 0.88 | DRD2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815771-B2 | Mechanochromic coating composition | PPG INDUSTRIES OHIO, INC. (US) | 2014-08-26 | — | — | US | disclosed |
| US-8815771-B2 | Mechanochromic coating composition | PPG INDUSTRIES OHIO, INC. (US) | 2014-08-26 | — | — | US | disclosed |
| WO-2013158379-A1 | MECHANOCHROMIC COATING COMPOSITION | PPG INDUSTRIES OHIO, INC. (US) | 2013-10-24 | — | — | WO | disclosed |
| US-20130269445-A1 | MECHANOCHROMIC COATING COMPOSITION | PPG INDUSTRIES OHIO, INC. (US) | 2013-10-17 | — | — | US | disclosed |
| US-20130269445-A1 | MECHANOCHROMIC COATING COMPOSITION | PPG INDUSTRIES OHIO, INC. (US) | 2013-10-17 | — | — | US | disclosed |