Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 2/20 | 0.34 |
| ▸ | LDHB | P07195 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10581455 | 0.84 | PDE10A (0.37) | PDE10AP2RX3ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL16806284 | 0.81 | PDE10A (0.47) | PDE10AP2RX3ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL28729970 | 0.81 | LMNA (0.39) | PDE10AP2RX3ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL28729971 | 0.81 | PDE10A (0.41) | PDE10AP2RX3ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL9327401 | 0.77 | PDE10A (0.44) | PDE10AALDH1A1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL11782605 | 0.76 | PDE10A (0.43) | PDE10AALDH1A1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL15316166 | 0.73 | PDE10A (0.44) | PDE10AP2RX3ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL8541994 | 0.73 | PDE10A (0.36) | PDE10AP2RX3ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL15316165 | 0.73 | PDE10A (0.48) | PDE10AP2RX3ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL25451179 | 0.72 | PDE10A (0.41) | PDE10AP2RX3ALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9334716-B2 | Treatment fluids comprising a hydroxypyridinecarboxylic acid and methods for use thereof | HALLIBURTON ENERGY SERVICES, INC. (US) | 2016-05-10 | — | — | US | disclosed |
| US-20130269941-A1 | Treatment Fluids Comprising a Hydroxypyridinecarboxylic Acid and Methods for Use Thereof | HALLIBURTON ENERGY SERVICES, INC. | 2013-10-17 | — | — | US | disclosed |