SCHEMBL15316166

SCHEMBL15316166

Cc1nc(C)c(C(=O)O)c(O)c1C

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 2/20 0.44
LDHA P00338 2/20 0.38
LDHB P07195 2/20 0.38
P2RX3 P56373 7/20 0.38
ALDH1A1 P00352 2/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
HTT P42858 2/20 0.34
TSHR P16473 1/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP3A4 P08684 1/20 0.33
ACHE P22303 1/20 0.33
GLRA3 O75311 1/20 0.33
GLRB P48167 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26967850 0.88 P2RX3 (0.41) PDE10ALDHALDHBP2RX3ALDH1A1
SCHEMBL17384120 0.82 SMN1; SMN2 (0.41) PDE10AALDH1A1SMN1; SMN2KMT2AMEN1
SCHEMBL15316165 0.82 PDE10A (0.48) PDE10ALDHALDHBP2RX3ALDH1A1
SCHEMBL31633610 0.81 PDE10A (0.52) PDE10AP2RX3ALDH1A1MAPK1SMN1; SMN2
SCHEMBL16806284 0.81 PDE10A (0.47) PDE10AP2RX3ALDH1A1MAPK1SMN1; SMN2
SCHEMBL8874663 0.81 PDE10A (0.52) PDE10AP2RX3ALDH1A1MAPK1SMN1; SMN2
SCHEMBL72281 0.80 PDE10A (0.45) PDE10ALDHALDHBALDH1A1MAPK1
SCHEMBL28462818 0.78 ALDH1A1 (0.41) PDE10AP2RX3ALDH1A1MAPK1SMN1; SMN2
SCHEMBL30174318 0.78 ALDH1A1 (0.39) PDE10ALDHALDHBP2RX3ALDH1A1
SCHEMBL27218056 0.78 P2RX3 (0.39) PDE10AP2RX3ALDH1A1SMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9334716-B2 Treatment fluids comprising a hydroxypyridinecarboxylic acid and methods for use thereof HALLIBURTON ENERGY SERVICES, INC. (US) 2016-05-10 US disclosed
US-20130269941-A1 Treatment Fluids Comprising a Hydroxypyridinecarboxylic Acid and Methods for Use Thereof HALLIBURTON ENERGY SERVICES, INC. 2013-10-17 US disclosed