SCHEMBL15316645

SCHEMBL15316645

CCCC1CCC(/C=C/C2CCC(C3CCC(COc4ccc(C)c(F)c4F)CC3)CC2)CC1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.33
HTR2A P28223 2/20 0.31
HTR2C P28335 2/20 0.31
HTR2B P41595 2/20 0.31
PDE4B Q07343 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16871478 0.93 RIPK1 (0.37) RIPK1HTR2AHTR2CHTR2BPDE4B
SCHEMBL26277357 0.93 RIPK1 (0.37) RIPK1HTR2AHTR2CHTR2BPDE4B
SCHEMBL15220735 0.92 RIPK1 (0.35) RIPK1HTR2AHTR2CHTR2BPDE4B
SCHEMBL17357023 0.89 RIPK1 (0.39) RIPK1HTR2AHTR2CHTR2BPDE4B
SCHEMBL13417689 0.87 HTR2A (0.33) RIPK1HTR2AHTR2CHTR2BPDE4B
SCHEMBL16807233 0.87 HTR2A (0.33) RIPK1HTR2AHTR2CHTR2BPDE4B
SCHEMBL9925019 0.86 HTR2A (0.32) RIPK1HTR2AHTR2CHTR2B
SCHEMBL9925024 0.86 HTR2A (0.32) RIPK1HTR2AHTR2CHTR2B
SCHEMBL26277391 0.86 RIPK1 (0.39) RIPK1HTR2AHTR2CHTR2BPDE4B
SCHEMBL24170502 0.86 RIPK1 (0.41) RIPK1HTR2AHTR2CHTR2BPDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9090825-B2 Cyclohexene-3,6-diyl compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-07-28 US disclosed
US-8956552-B2 Cyclohexene-3,6-diyl compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-20130270480-A1 CYCLOHEXENE-3,6-DIYL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION 2013-10-17 US disclosed