SCHEMBL15317255

SCHEMBL15317255

c1ccc(-n2c3ccccc3c3cc(-c4ccc5c(c4)c4ccccc4n5-c4cccc(-c5ccc6c(c5)c5ccncc5n6-c5ccc6oc7ccccc7c6c5)c4)ccc32)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
BTK Q06187 3/20 0.35
PIK3CD O00329 2/20 0.35
PIK3CA P42336 2/20 0.35
PIK3CB P42338 2/20 0.35
PIK3CG P48736 2/20 0.35
CDK4 P11802 2/20 0.35
CDK6 Q00534 2/20 0.35
PIK3R1 P27986 1/20 0.35
MTOR P42345 1/20 0.35
PLA2G2A P14555 2/20 0.34
PLA2G4A P47712 2/20 0.34
PLA2G10 O15496 1/20 0.34
DYRK1A Q13627 2/20 0.33
NPY5R Q15761 1/20 0.32
RAC2 P15153 1/20 0.32
RAC3 P60763 1/20 0.32
CDC42 P60953 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17809042 0.97 KDM4E (0.39) KDM4EATML3MBTL1BTKPIK3CD
SCHEMBL12114625 0.96 BTK (0.36) KDM4EATML3MBTL1BTKPIK3CD
SCHEMBL20715251 0.94 KDM4E (0.38) KDM4EATML3MBTL1BTKPIK3CD
SCHEMBL15317167 0.93 KDM4E (0.39) KDM4EATML3MBTL1BTKPIK3CD
SCHEMBL2628338 0.93 BTK (0.38) KDM4EATML3MBTL1BTKPIK3CD
SCHEMBL15945683 0.93 PLA2G2A (0.38) KDM4EATML3MBTL1BTKPIK3CD
SCHEMBL2628386 0.93 BTK (0.38) KDM4EATML3MBTL1BTKPIK3CD
SCHEMBL804571 0.93 BTK (0.38) KDM4EATML3MBTL1BTKPIK3CD
SCHEMBL804875 0.93 BTK (0.38) KDM4EATML3MBTL1BTKPIK3CD
SCHEMBL12126338 0.92 PLA2G2A (0.35) KDM4EATML3MBTL1BTKPIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9923151-B2 Material for organic electroluminescent elements, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-03-20 US disclosed
US-9923151-B2 Material for organic electroluminescent elements, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-03-20 US disclosed
US-20130270540-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-10-17 US disclosed
US-20130270540-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-10-17 US disclosed