SCHEMBL12126338

SCHEMBL12126338

c1cc(-c2cc(-c3ccc4oc5ccccc5c4c3)cc(-n3c4ccccc4c4ccccc43)c2)cc(-c2ccc3oc4ccc(-n5c6ccccc6c6ccncc65)cc4c3c2)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.35
PLA2G4A P47712 3/20 0.35
PLA2G10 O15496 1/20 0.35
BTK Q06187 3/20 0.35
PIK3CD O00329 2/20 0.35
PIK3CA P42336 2/20 0.35
PIK3CB P42338 2/20 0.35
PIK3CG P48736 2/20 0.35
PGR P06401 1/20 0.34
PIK3R1 P27986 1/20 0.34
MTOR P42345 1/20 0.34
NPC1 O15118 2/20 0.32
MAPT P10636 2/20 0.32
KDM4E B2RXH2 2/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2628349 0.98 NPC1 (0.33) PLA2G2APLA2G4APLA2G10BTKPIK3CD
SCHEMBL2628381 0.97 BTK (0.35) PLA2G2APLA2G4APLA2G10BTKPIK3CD
SCHEMBL804878 0.97 PLA2G2A (0.37) PLA2G2APLA2G4APLA2G10BTKPIK3CD
SCHEMBL804475 0.97 PLA2G2A (0.37) PLA2G2APLA2G4APLA2G10BTKPIK3CD
SCHEMBL804875 0.95 BTK (0.38) PLA2G2APLA2G4APLA2G10BTKPIK3CD
SCHEMBL804571 0.95 BTK (0.38) PLA2G2APLA2G4APLA2G10BTKPIK3CD
SCHEMBL2628386 0.95 BTK (0.38) PLA2G2APLA2G4APLA2G10BTKPIK3CD
SCHEMBL2628338 0.95 BTK (0.38) PLA2G2APLA2G4APLA2G10BTKPIK3CD
SCHEMBL10041356 0.94 PGR (0.38) PLA2G2APLA2G4APLA2G10BTKPIK3CD
SCHEMBL804799 0.93 NPC1 (0.35) PLA2G2APLA2G4APLA2G10BTKPIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8877352-B2 Biscarbazole derivative, material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-11-04 US disclosed
US-8877352-B2 Biscarbazole derivative, material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-11-04 US disclosed
US-20110278555-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed
US-20110278555-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110278555-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME UQCRB, OXA1L, HBS1L PLA2G2A 4424/4885PLA2G4A 4443/4885PLA2G10 4791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.