Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | SELE | P16581 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.30 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15317548 | 0.86 | MAPT (0.34) | MAPTRAB9AL3MBTL1CASP3SENP8 | |
| SCHEMBL12254124 | 0.84 | RAB9A (0.53) | MAPTRAB9AL3MBTL1CASP3SENP8 | |
| SCHEMBL12357550 | 0.84 | ALOX5AP (0.39) | MAPTRAB9AL3MBTL1CASP3SENP8 | |
| SCHEMBL12357290 | 0.84 | ALOX5AP (0.39) | MAPTRAB9AL3MBTL1CASP3SENP8 | |
| SCHEMBL12357809 | 0.84 | ALOX5AP (0.39) | MAPTRAB9AL3MBTL1CASP3SENP8 | |
| SCHEMBL14226680 | 0.83 | ALOX5AP (0.41) | MAPTRAB9AL3MBTL1CASP3SENP8 | |
| SCHEMBL12357814 | 0.82 | RARB (0.39) | MAPTRAB9AL3MBTL1CASP3SENP8 | |
| SCHEMBL12357557 | 0.82 | RARB (0.39) | MAPTRAB9AL3MBTL1CASP3SENP8 | |
| SCHEMBL15318780 | 0.81 | CYP11B1 (0.33) | — | |
| SCHEMBL12357554 | 0.81 | RARB (0.41) | MAPTRAB9AL3MBTL1CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133397-B2 | Tricyclic compound having a plurality of CF2O bonding groups, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2015-09-15 | — | — | US | disclosed |
| US-20130271719-A1 | TRICYCLIC COMPOUND HAVING A PLURALITY OF CF2O BONDING GROUPS, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2013-10-17 | — | — | US | disclosed |