Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7732585 | 0.88 | HTR2A (0.37) | FFAR1SLC7A5HSD11B1PPARGPPARA | |
| SCHEMBL7730566 | 0.87 | HTR2A (0.38) | FFAR1SLC7A5HSD11B1PPARGPPARA | |
| SCHEMBL15317549 | 0.86 | MAPT (0.36) | MAPTRAB9AL3MBTL1CASP3SENP8 | |
| SCHEMBL7735307 | 0.84 | PSEN1 (0.36) | CYP11B1CYP11B2FFAR1SLC7A5HSD11B1 | |
| SCHEMBL7732149 | 0.83 | PSEN1 (0.37) | CYP11B1CYP11B2FFAR1SLC7A5HSD11B1 | |
| SCHEMBL7735591 | 0.82 | DAO (0.39) | FFAR1HSD11B1PPARGPPARARARB | |
| SCHEMBL15318765 | 0.82 | CYP11B2 (0.39) | CYP11B1CYP11B2PDE2ASLC7A5PPARA | |
| SCHEMBL7735381 | 0.81 | KIF11 (0.47) | CYP11B1CYP11B2HSD11B1RARB | |
| SCHEMBL7729985 | 0.80 | KIF11 (0.38) | SENP8SENP7SENP6CYP11B1CYP11B2 | |
| SCHEMBL7730438 | 0.79 | DAO (0.40) | CYP11B1CYP11B2FFAR1SLC7A5PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133397-B2 | Tricyclic compound having a plurality of CF2O bonding groups, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2015-09-15 | — | — | US | disclosed |
| US-20130271719-A1 | TRICYCLIC COMPOUND HAVING A PLURALITY OF CF2O BONDING GROUPS, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2013-10-17 | — | — | US | disclosed |