Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15317559 | 0.81 | RAB9A (0.40) | CYP2C9L3MBTL1RAB9AMAPTCASP3 | |
| SCHEMBL14226686 | 0.78 | RAB9A (0.42) | L3MBTL1RAB9AMAPTCASP3SENP8 | |
| SCHEMBL14226683 | 0.78 | RAB9A (0.37) | CYP3A4CYP2C9L3MBTL1RAB9AMAPT | |
| SCHEMBL15317528 | 0.77 | NPC1 (0.35) | CYP3A4CYP2C9RAB9APKMNPC1 | |
| SCHEMBL14226684 | 0.77 | MAPT (0.38) | CYP3A4CYP2C9CYP2C19L3MBTL1RAB9A | |
| SCHEMBL12357360 | 0.77 | ALOX5AP (0.44) | PCSK9CYP3A4L3MBTL1RAB9AMAPT | |
| SCHEMBL12254124 | 0.76 | RAB9A (0.53) | L3MBTL1RAB9AMAPTCASP3SENP8 | |
| SCHEMBL7731549 | 0.76 | PCSK9 (0.34) | PCSK9ALOX5PPARGAPLNR | |
| SCHEMBL15317549 | 0.76 | MAPT (0.36) | CYP3A4CYP2C9PPARGL3MBTL1RAB9A | |
| SCHEMBL7732511 | 0.76 | PPARG (0.35) | PCSK9ALOX5PPARGL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133397-B2 | Tricyclic compound having a plurality of CF2O bonding groups, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2015-09-15 | — | — | US | disclosed |
| US-9133397-B2 | Tricyclic compound having a plurality of CF2O bonding groups, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2015-09-15 | — | — | US | disclosed |
| US-20130271719-A1 | TRICYCLIC COMPOUND HAVING A PLURALITY OF CF2O BONDING GROUPS, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2013-10-17 | — | — | US | disclosed |
| US-20130271719-A1 | TRICYCLIC COMPOUND HAVING A PLURALITY OF CF2O BONDING GROUPS, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2013-10-17 | — | — | US | disclosed |