Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL121146 | 0.75 | TSHR (0.57) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL19770533 | 0.73 | TSHR (0.55) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL960129 | 0.73 | TSHR (0.55) | TSHRKMT2AMEN1LMNACA12 | |
| Dimethyl Succinate SCHEMBL28249858 | 0.72 | TSHR (0.93) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL29020346 | 0.72 | TSHR (0.60) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL15539411 | 0.72 | TSHR (0.60) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL1805516 | 0.71 | TSHR (0.52) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL521654 | 0.70 | TSHR (0.57) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL26454467 | 0.70 | TSHR (0.57) | TSHRKMT2AMEN1LMNACA12 | |
| Dimethyl Succinate SCHEMBL28054469 | 0.69 | TSHR (1.00) | TSHRKMT2AMEN1LMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9249013-B2 | Silicon hardmask layer for directed self-assembly | BREWER SCIENCE INC. (US) | 2016-02-02 | — | — | US | disclosed |
| US-20130273330-A1 | SILICON HARDMASK LAYER FOR DIRECTED SELF-ASSEMBLY | BREWER SCIENCE INC. (US) | 2013-10-17 | — | — | US | disclosed |