SCHEMBL121146

SCHEMBL121146

COC(=O)CC[Si](OC)(OC)OC

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.57
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
LMNA P02545 3/20 0.41
KDM4E B2RXH2 2/20 0.41
CA12 O43570 2/20 0.41
CA14 Q9ULX7 2/20 0.41
RECQL P46063 1/20 0.41
ALDH1A1 P00352 3/20 0.40
HSD17B10 Q99714 2/20 0.40
HTT P42858 2/20 0.40
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
MAPT P10636 1/20 0.40
TET2 Q6N021 1/20 0.38
EPHX2 P34913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6228812 0.86 TSHR (0.61) TSHRKMT2AMEN1LMNAKDM4E
SCHEMBL31368202 0.85 ALDH1A1 (0.46) TSHRRECQLALDH1A1
SCHEMBL11128153 0.82 TSHR (0.56) TSHRKMT2ALMNARECQLALDH1A1
SCHEMBL30985266 0.82 TSHR (0.56) TSHRKMT2ALMNARECQLALDH1A1
SCHEMBL19770540 0.82 TSHR (0.56) TSHRKMT2ALMNARECQLALDH1A1
SCHEMBL26454467 0.80 TSHR (0.57) TSHRKMT2AMEN1LMNAKDM4E
SCHEMBL960158 0.79 CYP1A2 (0.47) TSHRKMT2ALMNAALDH1A1HSD17B10
SCHEMBL1808059 0.79 TSHR (0.50) TSHRKMT2AMEN1LMNAKDM4E
SCHEMBL20077464 0.79 KMT2A (0.48) TSHRKMT2AMEN1LMNAKDM4E
SCHEMBL19770533 0.78 TSHR (0.55) TSHRKMT2AMEN1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 351 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12332239-B2 Magnetic removal or identification of damaged or compromised cells or cellular structures INGURAN, LLC (US) 2025-06-17 US claimed
US-20240134281-A1 EUV-INDUCED CONDENSATION OF POLYSILOXANE SOL-GEL THIN FILM BREWER SCIENCE, INC. 2024-04-25 US claimed
US-20230384302-A1 MAGNETIC REMOVAL OR IDENTIFICATION OF DAMAGED OR COMPROMISED CELLS OR CELLULAR STRUCTURES INGURAN, LLC (US) 2023-11-30 US claimed
US-11817317-B2 High-silicon-content wet-removable planarizing layer BREWER SCIENCE, INC. (US) 2023-11-14 US claimed
US-11662344-B2 Magnetic removal or identification of damaged or compromised cells or cellular structures INGURAN, LLC (US) 2023-05-30 US claimed
CN-113416402-B Polycarbonate composite resin and film and preparation method thereof 深圳市海枫茂光学科技有限公司 2023-04-11 CN claimed
CN-115613352-A Breathable down-proof fabric and preparation method thereof 余翔 2023-01-17 CN claimed
CN-114874626-A Crosslinked organic silicon insulating thermal interface material capable of being completely degraded, recycled and reunited and preparation method and application thereof 黑龙江省科学院石油化学研究院 2022-08-09 CN claimed
EP-4018261-A1 UNDERLAYERS FOR EUV LITHOGRAPHY Brewer Science Inc. (US) 2022-06-29 EP claimed
US-11361967-B2 Underlayers for EUV lithography BREWER SCIENCE, INC. (US) 2022-06-14 US claimed
US-20100278748-A1 NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING GENERAL ELECTRIC COMPANY (US) 2010-11-04 US claimed
WO-2010070600-A1 SURFACE MODIFICATION FOR CROSS-LINKING OR BREAKING INTERACTIONS WITH INJECTED FLUID SCHLUMBERGER CANADA LIMITED (CA) 2010-06-24 WO claimed
US-20100147515-A1 SURFACE MODIFICATION FOR CROSS-LINKING OR BREAKING INTERACTIONS WITH INJECTED FLUID SCHLUMBERGER TECHNOLOGY CORPORATION 2010-06-17 US claimed
CN-101302346-A Etch-resistant disilane and saturated hydrocarbon bridged silicon-containing polymers, method of making the same, and method of using the same CHEIL IND INC (KR) 2008-11-12 CN claimed
US-20080241748-A1 Etch-resistant disilane and saturated hydrocarbon bridged silicon-containing polymers, method of making the same, and method of using the same CHEIL INDUSTRIES, INC. (KR) 2008-10-02 US claimed
US-20070087025-A1 Reiteratively layered medical devices and method of preparing same FITZHUGH ANTHONY 2007-04-19 US claimed
WO-2004072140-A2 CROSSLINKED POLYESTER COPOLYMERS DUAN JIWEN F (US) 2004-08-26 WO claimed
EP-1436018-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2004-07-14 EP claimed
US-6706842-B1 Crosslinked polyester copolymers DUAN JIWEN F (US) 2004-03-16 US claimed
WO-2003026717-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2003-04-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070087025-A1 Reiteratively layered medical devices and method of preparing same NOS2, NOS1, NOS3 TSHR 2005/4885KMT2A 738/4885MEN1 314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.