SCHEMBL15319072

SCHEMBL15319072

O=C(C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)S(=O)(=O)NF

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.41
CA2 P00918 6/20 0.41
MMP1 P03956 6/20 0.41
MMP2 P08253 6/20 0.41
MMP9 P14780 6/20 0.41
MMP8 P22894 6/20 0.41
MMP13 P45452 6/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15318860 0.94 CA1 (0.38) CA1CA2MMP1MMP2MMP9
SCHEMBL15319212 0.85 CA1 (0.32) CA1CA2MMP1MMP2MMP9
SCHEMBL5829449 0.73 CA2 (0.62) CA1CA2MMP1MMP2MMP9
SCHEMBL18546646 0.72 CA2 (0.64) CA1CA2MMP1MMP2MMP9
SCHEMBL27780732 0.72 CA2 (0.64) CA1CA2MMP1MMP2MMP9
SCHEMBL15319193 0.72 CA2 (0.43) CA1CA2MMP1MMP2MMP9
SCHEMBL20473123 0.72 CA2 (0.64) CA1CA2MMP1MMP2MMP9
SCHEMBL15318988 0.70 CA1 (0.41) CA1CA2MMP1MMP2MMP9
SCHEMBL2019285 0.68 THRB (0.55) CA1CA2MMP1MMP2MMP9
SCHEMBL15319199 0.67 CA1 (0.38) CA1CA2MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2834251-A1 IONIC COMPOUNDS HAVING A SILYLOXY GROUP Hydro-Québec (CA) 2015-02-11 EP claimed
WO-2013149349-A1 IONIC COMPOUNDS HAVING A SILYLOXY GROUP HYDRO-QUéBEC (CA) 2013-10-10 WO claimed
EP-2834251-A1 IONIC COMPOUNDS HAVING A SILYLOXY GROUP Hydro-Québec (CA) 2015-02-11 EP disclosed
WO-2013149349-A1 IONIC COMPOUNDS HAVING A SILYLOXY GROUP HYDRO-QUéBEC (CA) 2013-10-10 WO disclosed