Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22495180 | 0.84 | CA1 (0.33) | CA1CA2CA7 | |
| SCHEMBL3919305 | 0.82 | CA1 (0.32) | CA1CA2CA7 | |
| SCHEMBL3920257 | 0.82 | CA1 (0.32) | CA1CA2CA7 | |
| SCHEMBL3922189 | 0.82 | CA1 (0.32) | CA1CA2CA7 | |
| SCHEMBL3927514 | 0.82 | CA1 (0.32) | CA1CA2CA7 | |
| SCHEMBL13685030 | 0.81 | TSHR (0.30) | CA1CA2CA7TSHR | |
| SCHEMBL8906227 | 0.78 | TDP1 (0.43) | — | |
| SCHEMBL7452694 | 0.77 | CA1 (0.50) | CA1CA2CA7 | |
| SCHEMBL23045157 | 0.77 | CA1 (0.42) | CA1CA2CA7 | |
| SCHEMBL11766137 | 0.77 | CA1 (0.42) | CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10106833-B2 | Methods and compounds for identifying glycosyltransferase inhibitors | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-10-23 | — | — | US | disclosed |
| EP-2850090-B1 | CHEMOENZYMATIC METHODS FOR SYNTHESIZING MOENOMYCIN ANALOGS | HARVARD COLLEGE (US) | 2018-10-03 | — | — | EP | disclosed |
| US-9902985-B2 | Chemoenzymatic methods for synthesizing moenomycin analogs | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-02-27 | — | — | US | disclosed |
| US-20160280732-A1 | MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-09-29 | — | — | US | disclosed |
| US-9273084-B2 | Moenomycin analogs, methods of synthesis, and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-03-01 | — | — | US | disclosed |
| US-20150119354-A1 | MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-04-30 | — | — | US | disclosed |
| US-20150119561-A1 | CHEMOENZYMATIC METHODS FOR SYNTHESIZING MOENOMYCIN ANALOGS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-04-30 | — | — | US | disclosed |
| EP-2850090-A1 | CHEMOENZYMATIC METHODS FOR SYNTHESIZING MOENOMYCIN ANALOGS | President and Fellows of Harvard College (US) | 2015-03-25 | — | — | EP | disclosed |
| EP-2850091-A1 | METHODS AND COMPOUNDS FOR IDENTIFYING GLYCOSYLTRANSFERASE INHIBITORS | President and Fellows of Harvard College (US) | 2015-03-25 | — | — | EP | disclosed |
| US-20150079618-A1 | METHODS AND COMPOUNDS FOR IDENTIFYING GLYCOSYLTRANSFERASE INHIBITORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-03-19 | — | — | US | disclosed |
| EP-2834254-A2 | MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | President and Fellows of Harvard College (US) | 2015-02-11 | — | — | EP | disclosed |
| WO-2013151697-A1 | METHODS AND COMPOUNDS FOR IDENTIFYING GLYCOSYLTRANSFERASE INHIBITORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-10-10 | — | — | WO | disclosed |
| WO-2013152279-A1 | CHEMOENZYMATIC METHODS FOR SYNTHESIZING MOENOMYCIN ANALOGS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-10-10 | — | — | WO | disclosed |
| WO-2013152277-A2 | MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119561-A1 | CHEMOENZYMATIC METHODS FOR SYNTHESIZING MOENOMYCIN ANALOGS | CYP51A1, COASY, MRM1 | CA1 3559/4885CA2 4035/4885CA7 899/4885 |
| US-20150119354-A1 | MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | RDX, RPS4X, RPS4Y1 | CA1 4425/4885CA2 3809/4885CA7 496/4885 |
| US-10106833-B2 | Methods and compounds for identifying glycosyltransferase inhibitors | MAGT1, GALNT1, NMT1 | CA1 4089/4885CA2 3359/4885CA7 978/4885 |
| US-20160280732-A1 | MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | RDX, RPS4X, MLX | CA1 4279/4885CA2 3441/4885CA7 362/4885 |
| US-20150079618-A1 | METHODS AND COMPOUNDS FOR IDENTIFYING GLYCOSYLTRANSFERASE INHIBITORS | MAGT1, GALNT1, NMT1 | CA1 4089/4885CA2 3359/4885CA7 978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.