Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | SLC5A2 | P31639 | 6/20 | 0.45 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL153203 | 1.00 | ATM (0.47) | ATMEPHX2SLC5A2SLC5A1MEN1 | |
| SCHEMBL153201 | 0.88 | SLC5A2 (0.37) | ATMEPHX2SLC5A2SLC5A1 | |
| SCHEMBL152729 | 0.83 | SLC28A3 (0.51) | ATMEPHX2SLC5A2SLC5A1MEN1 | |
| SCHEMBL152730 | 0.83 | SLC28A3 (0.51) | ATMEPHX2SLC5A2SLC5A1MEN1 | |
| SCHEMBL151978 | 0.82 | ATM (0.54) | ATMEPHX2SLC5A2SLC5A1MEN1 | |
| SCHEMBL154171 | 0.82 | ATM (0.54) | ATMEPHX2SLC5A2SLC5A1MEN1 | |
| SCHEMBL153288 | 0.81 | ATM (0.45) | ATMEPHX2SLC5A2SLC5A1MEN1 | |
| SCHEMBL156210 | 0.81 | POLB (0.47) | ATMEPHX2SLC5A2SLC5A1SLC28A3 | |
| SCHEMBL153289 | 0.81 | ATM (0.45) | ATMEPHX2SLC5A2SLC5A1MEN1 | |
| SCHEMBL156209 | 0.81 | POLB (0.47) | ATMEPHX2SLC5A2SLC5A1SLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940909-B2 | Indicator platform | BIOSYNTH AG (CH) | 2015-01-27 | — | — | US | disclosed |
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| US-20120058503-A1 | Novel Indicator Platform | BIOSYNTH AG (CH) | 2012-03-08 | — | — | US | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |