Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CPT2 | P23786 | 1/20 | 0.40 |
| ▸ | CPT1A | P50416 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | CRAT | P43155 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 8/20 | 0.32 |
| ▸ | CA2 | P00918 | 8/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carnitine SCHEMBL4284339 | 0.96 | SLC22A16 (0.57) | SLC22A16MAPTCPT2CPT1AMEN1 | |
| Carnitine SCHEMBL27500714 | 0.95 | SLC22A16 (0.56) | SLC22A16MAPTCPT2CPT1AMEN1 | |
| Carnitine SCHEMBL27500124 | 0.91 | SLC22A16 (0.51) | SLC22A16MAPTCPT2CPT1AMEN1 | |
| Creatine SCHEMBL15322407 | 0.77 | MEN1 (0.45) | SLC22A16MAPTMEN1KMT2ACYP1A2 | |
| Fosfocreatine SCHEMBL4277995 | 0.77 | SLC22A16 (0.50) | SLC22A16MAPTCPT2CPT1AMEN1 | |
| Propionyl-Carnitine SCHEMBL4279796 | 0.77 | MEN1 (0.65) | MAPTCPT2CPT1AMEN1KMT2A | |
| Creatine SCHEMBL5422993 | 0.77 | MEN1 (0.41) | SLC22A16MAPTCPT2CPT1AMEN1 | |
| Creatine SCHEMBL27865596 | 0.76 | NOS3 (0.43) | NOS3NOS1NOS2CA1CA2 | |
| Fosfocreatine SCHEMBL4277999 | 0.76 | SLC22A16 (0.49) | SLC22A16MAPTCPT2CPT1AMEN1 | |
| Creatine SCHEMBL4137956 | 0.75 | NOS3 (0.41) | NOS3NOS1NOS2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836832-A1 | EARLY TRIMESTER SCREENING FOR EARLY- AND LATE-ONSET PREECLAMPSIA | Wayne State University (US) | 2015-02-18 | — | — | EP | disclosed |
| WO-2013155458-A1 | EARLY TRIMESTER SCREENING FOR EARLY- AND LATE-ONSET PREECLAMPSIA | WAYNE STATE UNIVERSITY (US) | 2013-10-17 | — | — | WO | disclosed |