Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CCL2 | P13500 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25218430 | 0.85 | HTR2A (0.39) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 | |
| SCHEMBL9056492 | 0.83 | HTR2A (0.38) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 | |
| SCHEMBL8732534 | 0.83 | HTR2A (0.38) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 | |
| Lithium SCHEMBL7825806 | 0.82 | HTR2A (0.36) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 | |
| SCHEMBL23100802 | 0.82 | HTR2A (0.36) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 | |
| SCHEMBL7825802 | 0.82 | HTR2A (0.36) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 | |
| SCHEMBL7385664 | 0.81 | HTR6 (0.37) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 | |
| SCHEMBL11555147 | 0.80 | MTNR1A (0.30) | — | |
| Hydrochloric Acid SCHEMBL7822196 | 0.80 | HTR2A (0.35) | HTR2AHTR6CYP2D6RET | |
| SCHEMBL629577 | 0.80 | POLB (0.36) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836576-A1 | AMINE TERMINATED AND HYDROXYL TERMINATED POLYETHER DISPERSANTS | The Lubrizol Corporation (US) | 2015-02-18 | — | — | EP | disclosed |
| WO-2014023853-A2 | TERTIARY AMINES FOR REDUCING INJECTOR NOZZLE FOULING AND MODIFYING FRICTION IN DIRECT INJECTION SPARK IGNITION ENGINES | BASF SE (DE) | 2014-02-13 | — | — | WO | disclosed |
| WO-2013154958-A1 | AMINE TERMINATED AND HYDROXYL TERMINATED POLYETHER DISPERSANTS | THE LUBRIZOL CORPORATION (US) | 2013-10-17 | — | — | WO | disclosed |