Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 10/20 | 0.53 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.53 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510869 | 0.91 | LPAR3 (0.56) | LPAR3LPAR2LPAR1 | |
| SCHEMBL7184210 | 0.84 | LPAR3 (0.56) | LPAR3LPAR2LPAR1HTTLPAR5 | |
| SCHEMBL7107080 | 0.84 | LPAR3 (0.56) | LPAR3LPAR2LPAR1HTTLPAR5 | |
| SCHEMBL27585706 | 0.79 | LPAR3 (0.50) | LPAR3LPAR2LPAR1LPAR5CYP3A4 | |
| SCHEMBL11687397 | 0.77 | CYP3A4 (0.52) | LPAR3LPAR2LPAR1LPAR5CYP3A4 | |
| SCHEMBL7551578 | 0.77 | LPAR3 (0.59) | LPAR3LPAR2LPAR1 | |
| SCHEMBL4454776 | 0.76 | CYP3A4 (0.50) | LPAR3LPAR2LPAR1LPAR5CYP3A4 | |
| SCHEMBL28131538 | 0.75 | LPAR3 (0.57) | LPAR3LPAR2LPAR1LPAR5CYP3A4 | |
| SCHEMBL2782421 | 0.75 | MAPT (0.46) | LPAR3LPAR2LPAR1LPAR5DNM1 | |
| SCHEMBL25870 | 0.75 | MAPT (0.46) | LPAR3LPAR2LPAR1LPAR5DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023039415-A2 | IODIDE NANOPARTICLES AND COMPOSITIONS OF METHODS OF USE THEREOF | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2023-03-16 | — | — | WO | disclosed |
| WO-2019161263-A1 | LIPID-SURFACTANT NANOPARTICLES FOR DRUG DELIVERY AND METHODS OF MAKING AND USES THEREOF | OHIO STATE INNOVATION FOUNDATION (US) | 2019-08-22 | — | — | WO | disclosed |
| EP-2836234-A1 | VEHICLES FOR CONTROLLED DELIVERY OF DIFFERENT PHARMACEUTICAL AGENTS | Yale University (US) | 2015-02-18 | — | — | EP | disclosed |
| WO-2013155487-A1 | VEHICLES FOR CONTROLLED DELIVERY OF DIFFERENT PHARMACEUTICAL AGENTS | YALE UNIVERSITY (US) | 2013-10-17 | — | — | WO | disclosed |