SCHEMBL6510869

SCHEMBL6510869

CCCCCCCCC=CCCCCCCCCOP(=O)(OCCCCCCCCC=CCCCCCCCC)C(O)CN

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 10/20 0.56
LPAR2 Q9HBW0 7/20 0.56
LPAR1 Q92633 6/20 0.56
P2RY10 O00398 2/20 0.48
S1PR4 O95977 2/20 0.46
S1PR1 P21453 2/20 0.46
S1PR3 Q99500 2/20 0.46
S1PR5 Q9H228 2/20 0.46
S1PR2 O95136 1/20 0.46
ALDH1A1 P00352 1/20 0.46
TSPO P30536 1/20 0.46
TMEM97 Q5BJF2 1/20 0.46
SIGMAR1 Q99720 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15323486 0.91 LPAR3 (0.53) LPAR3LPAR2LPAR1
SCHEMBL7551578 0.87 LPAR3 (0.59) LPAR3LPAR2LPAR1P2RY10S1PR4
SCHEMBL1367616 0.79 LPAR1 (0.52) LPAR3LPAR2LPAR1P2RY10
SCHEMBL7107080 0.76 LPAR3 (0.56) LPAR3LPAR2LPAR1
SCHEMBL7184210 0.76 LPAR3 (0.56) LPAR3LPAR2LPAR1
SCHEMBL23016698 0.76 LPAR3 (0.93) LPAR3LPAR2LPAR1S1PR4S1PR1
SCHEMBL10934225 0.76 LPAR3 (0.64) LPAR3LPAR2LPAR1P2RY10
SCHEMBL7781151 0.76 LPAR3 (0.93) LPAR3LPAR2LPAR1S1PR4S1PR1
SCHEMBL4981351 0.76 LPAR3 (0.93) LPAR3LPAR2LPAR1S1PR4S1PR1
SCHEMBL193119 0.76 LPAR3 (0.93) LPAR3LPAR2LPAR1S1PR4S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050112661-A1 Methods for delivering nucleic acid molecules into cells and assessment thereof GLAXO GROUP LIMITED (GB) 2005-05-26 US disclosed